Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.30 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.30 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6853054 | 0.84 | CYP1A2 (0.33) | TDP1ALDH1A1TSHRHSD17B10HSD11B1 | |
| SCHEMBL6939002 | 0.75 | HSD11B1 (0.42) | HSD11B1ALOX5APGRIN2DGRIN3BGRIN1 | |
| SCHEMBL6852814 | 0.68 | HPRT1 (0.39) | HPRT1TDP1ALDH1A1CYP2A6TSHR | |
| SCHEMBL3043614 | 0.67 | SLC6A3 (0.41) | ALDH1A1LMNAMAPTMAPK1GRIN2D | |
| Phosphine SCHEMBL28240146 | 0.66 | SLC6A3 (0.41) | ALDH1A1LMNAMAPTMAPK1GRIN2D | |
| Phenanthrene SCHEMBL28522812 | 0.65 | ALDH1A1 (0.67) | HPRT1TDP1ALDH1A1CYP2A6TSHR | |
| SCHEMBL6850950 | 0.64 | HSD11B1 (0.41) | HSD11B1MAPK1ALOX5APGRIN2DGRIN3B | |
| SCHEMBL4846118 | 0.64 | GRIN2D (0.47) | ALDH1A1HSD11B1LMNAGRIN2DGRIN3B | |
| SCHEMBL11547069 | 0.64 | HSD11B1 (0.41) | HSD11B1ALOX5APGRIN2DGRIN3BGRIN1 | |
| SCHEMBL28877620 | 0.64 | HSD11B1 (0.41) | HSD11B1ALOX5APGRIN2DGRIN3BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6777111-B1 | HEAT ENDURANCE; LOW CRYSTALLINITY; EMPLOYING CONDENSED RING DERIVATIVE | KABUSHIKI KAISHA CHUO KENKYUSHO (JP) | 2004-08-17 | — | — | US | disclosed |