Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | MGAM | O43451 | 2/20 | 0.47 |
| ▸ | SI | P14410 | 2/20 | 0.47 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8757316 | 0.84 | ALDH1A1 (0.46) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL3654803 | 0.80 | ALDH1A1 (0.62) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL11620981 | 0.76 | DCUN1D1 (0.44) | GAAALDH1A1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL27260167 | 0.74 | ALDH1A1 (0.57) | HSD17B10GAAALDH1A1TDP1KMT2A | |
| SCHEMBL16799501 | 0.74 | MEN1 (0.48) | HSD17B10GAAMGAMSIMGAM2 | |
| SCHEMBL6846876 | 0.73 | KMT2A (0.44) | HSD17B10GAAMGAMSIMGAM2 | |
| SCHEMBL3170513 | 0.72 | DHFR (0.38) | HSD17B10GAAKMT2AMEN1LMNA | |
| SCHEMBL30564320 | 0.72 | HSD17B10 (0.69) | HSD17B10GAAMGAMSIMGAM2 | |
| SCHEMBL2360248 | 0.72 | HSD17B10 (0.69) | HSD17B10GAAMGAMSIMGAM2 | |
| SCHEMBL17785663 | 0.72 | TDP1 (0.42) | HSD17B10GAAMGAMSIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1154637-C | Method for producing substituted pyrazoles | �����ɷ� | 2004-06-23 | — | — | CN | disclosed |
| EP-1021416-B1 | METHOD FOR PRODUCING SUBSTITUTED PYRAZOLES | BASF AG (DE) | 2004-05-19 | — | — | EP | disclosed |
| EP-1175406-A1 | IMIDAZOLINE DERIVATIVES AS ALPHA-1A ADRENOCEPTOR LIGANDS | GLAXO GROUP LIMITED (GB) | 2002-01-30 | — | — | EP | disclosed |
| US-6229022-B1 | REACTING CARBONYL COMPOUNDS WITH HYDRAZINE, ITS HYDRATE OR SALTS IN THE PRESENCE OF SULFURIC ACID AND IODINE OR AN IODINE LIBERATING COMPOUND | BASF AKTIENGESELLSCHAFT (DE) | 2001-05-08 | — | — | US | disclosed |
| WO-2000066563-A1 | IMIDAZOLINE DERIVATIVES AS ALPHA-1A ADRENOCEPTOR LIGANDS | GLAXO GROUP LIMITED (GB) | 2000-11-09 | — | — | WO | disclosed |
| EP-1021416-A1 | METHOD FOR PRODUCING SUBSTITUTED PYRAZOLES | BASF AKTIENGESELLSCHAFT (DE) | 2000-07-26 | — | — | EP | disclosed |
| CN-1261351-A | Process for preparing substituted pyrazoles | BASF AG (DE) | 2000-07-26 | — | — | CN | disclosed |
| WO-1998058914-A1 | METHOD FOR PRODUCING SUBSTITUTED PYRAZOLES | BASF AKTIENGESELLSCHAFT (DE) | 1998-12-30 | — | — | WO | disclosed |