Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.43 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21322050 | 0.84 | GAA (0.50) | GAARAB9AMAPTNPC1L3MBTL1 | |
| SCHEMBL9091925 | 0.79 | MAPT (0.54) | GAARAB9AMAPTNPC1L3MBTL1 | |
| SCHEMBL8619179 | 0.79 | KCNH3 (0.43) | GAAMAPTMAPK1NPSR1CA2 | |
| SCHEMBL11037489 | 0.77 | NPC1 (0.55) | GAARAB9AMAPTNPC1KDM4E | |
| SCHEMBL11510051 | 0.76 | KDM4E (0.49) | GAARAB9AMAPTNPC1L3MBTL1 | |
| SCHEMBL6921827 | 0.75 | MAPT (0.42) | GAARAB9AMAPTNPC1L3MBTL1 | |
| SCHEMBL2545271 | 0.74 | KCNH3 (0.40) | GAARAB9AMAPTL3MBTL1MAPK1 | |
| SCHEMBL16758732 | 0.74 | KCNH3 (0.40) | GAARAB9AMAPTL3MBTL1MAPK1 | |
| SCHEMBL10584523 | 0.74 | KCNH3 (0.40) | GAARAB9AMAPTL3MBTL1MAPK1 | |
| SCHEMBL7793204 | 0.73 | GAA (0.76) | GAARAB9AMAPTNPC1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1081152-B1 | Triaza-cryptand and method of determining an alkali ion | HOFFMANN LA ROCHE (CH) | 2004-10-06 | — | — | EP | disclosed |
| US-6211359-B1 | QUANTITATIVE ANALYSIS | AVL MEDICAL INSTRUMENTS (CH) | 2001-04-03 | — | — | US | disclosed |
| EP-1081152-A1 | Triaza-cryptand and method of determining an alkali ion | AVL Medical Instruments AG (CH) | 2001-03-07 | — | — | EP | disclosed |