Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.58 |
| ▸ | DRD4 | P21917 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | WDR5 | P61964 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | PPARD | Q03181 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9808215 | 0.86 | LMNA (0.67) | DRD2DRD4LMNAMAPK1HTT | |
| SCHEMBL1685432 | 0.84 | DRD2 (0.62) | DRD2DRD4LMNAMAPK1HTT | |
| SCHEMBL9774806 | 0.82 | DRD2 (0.60) | DRD2DRD4LMNAMAPK1HTT | |
| SCHEMBL197632 | 0.81 | KMT2A (0.76) | DRD2DRD4LMNAMAPK1HTT | |
| SCHEMBL2963485 | 0.81 | DRD2 (0.58) | DRD2DRD4LMNAMAPK1HTT | |
| SCHEMBL6470787 | 0.81 | DRD2 (0.58) | DRD2DRD4LMNAMAPK1HTT | |
| SCHEMBL5825855 | 0.81 | KMT2A (0.60) | DRD2DRD4LMNAMAPK1HTT | |
| SCHEMBL6846799 | 0.81 | DRD2 (0.58) | DRD2DRD4LMNAMAPK1HTT | |
| SCHEMBL29434730 | 0.81 | DRD2 (0.58) | DRD2DRD4LMNAMAPK1HTT | |
| SCHEMBL31267597 | 0.80 | DRD2 (0.54) | DRD2DRD4LMNAMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6756384-B2 | TREATMENT OF DISEASES AND DISORDERS RELATED TO THE HISTAMINE H3 RECEPTOR. | NOVO NORDISK A/S (DK) | 2004-06-29 | — | — | US | disclosed |