SCHEMBL197632

SCHEMBL197632

CCCCOc1cccc(Cl)c1

nearest known ligand 0.76

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.76
KCNH2 Q12809 1/20 0.61
DRD2 P14416 1/20 0.58
DRD4 P21917 1/20 0.58
FAAH O00519 1/20 0.58
LMNA P02545 1/20 0.57
MAPK1 P28482 1/20 0.57
HTT P42858 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
KDM4E B2RXH2 2/20 0.56
TSHR P16473 1/20 0.54
MEN1 O00255 1/20 0.54
PPARG P37231 1/20 0.54
PPARD Q03181 1/20 0.54
LTA4H P09960 1/20 0.53
HRH3 Q9Y5N1 5/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methyl Alcohol SCHEMBL27541418 0.96 KMT2A (0.71) KMT2AKCNH2DRD2DRD4FAAH
Dimethylamine SCHEMBL3445328 0.95 KMT2A (0.74) KMT2AKCNH2DRD2DRD4FAAH
SCHEMBL8551026 0.94 KMT2A (0.73) KMT2AKCNH2DRD2DRD4FAAH
SCHEMBL196962 0.90 KMT2A (0.68) KMT2AKCNH2DRD2DRD4FAAH
SCHEMBL9808215 0.86 LMNA (0.67) KMT2AKCNH2DRD2DRD4LMNA
SCHEMBL4397448 0.86 TSHR (0.63) KMT2AMAPK1SMN1; SMN2TSHRLTA4H
SCHEMBL11663247 0.85 KMT2A (0.58) KMT2AKCNH2DRD2DRD4FAAH
SCHEMBL1685432 0.84 DRD2 (0.62) KMT2AKCNH2DRD2DRD4LMNA
SCHEMBL11504437 0.83 KMT2A (0.56) KMT2AFAAHLMNAMAPK1KDM4E
SCHEMBL9774806 0.82 DRD2 (0.60) KMT2AKCNH2DRD2DRD4LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3632892-B1 METHOD FOR PRODUCING 3-ARYLPROPIONAMIDE COMPOUND SUMITOMO CHEMICAL CO (JP) 2024-07-31 EP disclosed
CN-110799490-B 3-arylpropionamide compound and method for producing 3-arylpropionate compound 住友化学株式会社 2023-05-02 CN disclosed
US-11028056-B2 Method for producing 3-arylpropionamide compound and 3-arylpropionic acid ester compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2021-06-08 US disclosed
US-20200165209-A1 METHOD FOR PRODUCING 3-ARYLPROPIONAMIDE COMPOUND AND 3-ARYLPROPIONIC ACID ESTER COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2020-05-28 US disclosed
EP-3632892-A1 METHOD FOR PRODUCING 3-ARYLPROPIONAMIDE COMPOUND AND 3-ARYLPROPIONIC ACID ESTER COMPOUND Sumitomo Chemical Company, Limited (JP) 2020-04-08 EP disclosed
CN-110799490-A Process for producing 3-arylpropionamide compound and process for producing 3-arylpropionate compound 住友化学株式会社 2020-02-14 CN disclosed
CN-104230682-B A kind of method preparing alkoxyl iodobenzene 河南科技大学 2016-09-07 CN disclosed
US-9079901-B2 Fused heterocyclic compounds as ion channel modulators GILEAD SCIENCES, INC. (US) 2015-07-14 US disclosed
US-20150080370-A1 FUSED HETEROCYCLIC COMPOUNDS AS ION CHANNEL MODULATORS GILEAD SCIENCES, INC. 2015-03-19 US disclosed
CN-104230682-A Method for preparing alkoxy iodobenzene UNIV HENAN SCIENCE & TECH 2014-12-24 CN disclosed
US-20100184978-A1 BIPYRIDINE COMPOUND, TRANSITION METAL COMPLEX, AND METHOD FOR PRODUCTION OF CONJUGATED AROMATIC COMPOUND USING THE TRANSITION METAL COMPLEX SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-07-22 US disclosed
CN-101772508-A Bipyridine compound, transition metal complex, and method for production of conjugated aromatic compound using the transition metal complex SUMITOMO CHEMICAL CO 2010-07-07 CN disclosed
EP-2192124-A1 TRANSITION METAL COMPLEX AND PROCESS FOR PRODUCING CONJUGATED AROMATIC COMPOUND WITH THE TRANSITION METAL COMPLEX Sumitomo Chemical Company, Limited (JP) 2010-06-02 EP disclosed
US-20100087680-A1 METHOD FOR PRODUCING BIARYL COMPOUND SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2010-04-08 US disclosed
EP-2172470-A1 BIPYRIDINE COMPOUND, TRANSITION METAL COMPLEX, AND METHOD FOR PRODUCTION OF CONJUGATED AROMATIC COMPOUND USING THE TRANSITION METAL COMPLEX Sumitomo Chemical Company, Limited (JP) 2010-04-07 EP disclosed
US-7521581-B2 Catalyst composition and process for producing cross-coupled compound using same TOSOH CORPORATION (JP) 2009-04-21 US disclosed
EP-1707263-B1 Catalyst composition comprising an alkylene diamine-nickel complex and process for producing a cross-coupled compound using the same TOSOH CORP (JP) 2009-02-25 EP disclosed
EP-1914221-A1 PROCESS FOR PRODUCING BIARYL COMPOUND Sumitomo Chemical Company, Limited (JP) 2008-04-23 EP disclosed
US-20060224011-A1 Catalyst composition and process for producing cross-coupled compound using same TOSOH CORPORATION 2006-10-05 US disclosed
EP-1707263-A1 Catalyst composition comprising an alkylene diamine-nickel complex and process for producing a cross-coupled compound using the same Tosoh Corporation (JP) 2006-10-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150080370-A1 FUSED HETEROCYCLIC COMPOUNDS AS ION CHANNEL MODULATORS KCNJ2, KCNH2, CACNA1E KMT2A 3048/4885KCNH2 2/4885DRD2 1296/4885
US-20100184978-A1 BIPYRIDINE COMPOUND, TRANSITION METAL COMPLEX, AND METHOD FOR PRODUCTION OF CONJUGATED AROMATIC COMPOUND USING THE TRANSITION METAL COMPLEX C9, C5, AP2M1 KMT2A 2407/4885KCNH2 192/4885DRD2 170/4885
US-20100087680-A1 METHOD FOR PRODUCING BIARYL COMPOUND NISCH, BLVRB, BBOX1 KMT2A 1474/4885KCNH2 1145/4885DRD2 2087/4885
US-20200165209-A1 METHOD FOR PRODUCING 3-ARYLPROPIONAMIDE COMPOUND AND 3-ARYLPROPIONIC ACID ESTER COMPOUND AADAC, DDT, NAT1 KMT2A 861/4885KCNH2 1453/4885DRD2 1718/4885
US-20060224011-A1 Catalyst composition and process for producing cross-coupled compound using same C5, TST, PYM1 KMT2A 1683/4885KCNH2 234/4885DRD2 2856/4885
US-11028056-B2 Method for producing 3-arylpropionamide compound and 3-arylpropionic acid ester compound AADAC, DDT, NAT1 KMT2A 861/4885KCNH2 1453/4885DRD2 1718/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.