Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ATR | Q13535 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrrolidine SCHEMBL2219944 | 1.00 | — | — | |
| Pyrrolidine SCHEMBL8459727 | 0.97 | ALDH1A1 (0.47) | ALDH1A1CXCR4SMN1; SMN2NOS2MAPT | |
| Pyrrolidine SCHEMBL5823457 | 0.97 | ALDH1A1 (0.47) | ALDH1A1CXCR4SMN1; SMN2NOS2MAPT | |
| Piperidine SCHEMBL7564193 | 0.97 | ALDH1A1 (0.56) | ALDH1A1CXCR4SMN1; SMN2NOS2MAPT | |
| Piperidine SCHEMBL11035777 | 0.97 | ALDH1A1 (0.56) | ALDH1A1CXCR4SMN1; SMN2NOS2MAPT | |
| Piperidine SCHEMBL9749275 | 0.94 | ALDH1A1 (0.53) | ALDH1A1CXCR4SMN1; SMN2NOS2MAPT | |
| Piperidine SCHEMBL10726327 | 0.94 | ALDH1A1 (0.53) | ALDH1A1CXCR4SMN1; SMN2NOS2MAPT | |
| Aziridine SCHEMBL29603143 | 0.89 | — | — | |
| Piperidine SCHEMBL9644995 | 0.87 | ALDH1A1 (0.60) | ALDH1A1CXCR4SMN1; SMN2NOS2MAPT | |
| Piperazine SCHEMBL28283221 | 0.86 | HIF1A (0.46) | CXCR4SMN1; SMN2NOS2MAPTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109983085-B | Chromium-free coating composition having anticorrosive effect on metal substrate | 阿克佐诺贝尔国际涂料股份有限公司 | 2021-04-23 | — | — | CN | disclosed |
| CN-102176919-A | Methods and compositions for treatment of bone defects with placental cell populations | ANTHROGENESIS CORP | 2011-09-07 | — | — | CN | disclosed |
| US-6703031-B1 | OXIDATIVE STRESS INHIBITOR; RETARDING AGING OF SKIN | AJINOMOTO CO., INC. (JP) | 2004-03-09 | — | — | US | disclosed |
| CN-1311629-A | Inhibitors of transcription factor NF-KB | SMITHKLINE BEECHAM CORP (US) | 2001-09-05 | — | — | CN | disclosed |
| US-5821260-A | Treatment for atherosclerosis and other cardiovascular and inflammatory diseases | EMORY UNIVERSITY (US) | 1998-10-13 | — | — | US | disclosed |
| US-5783596-A | Treatment for atherosclerosis and other cardiovascular and inflammatory diseases | EMORY UNIVERSITY (US) | 1998-07-21 | — | — | US | disclosed |