Piperidine

Piperidine

SCHEMBL9749275

C.C.C.C.C.C1CCNCC1.NC(O)=S.NC(O)=S

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.53
CXCR4 P61073 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
KDM4E B2RXH2 1/20 0.30
MAPT P10636 1/20 0.30
KMT2A Q03164 1/20 0.30
ATM Q13315 1/20 0.30
NOS2 P35228 1/20 0.30
CYP2D6 P10635 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Piperidine SCHEMBL7564193 0.97 ALDH1A1 (0.56) ALDH1A1CXCR4SMN1; SMN2KDM4EMAPT
Piperidine SCHEMBL11035777 0.97 ALDH1A1 (0.56) ALDH1A1CXCR4SMN1; SMN2KDM4EMAPT
Piperidine SCHEMBL10726327 0.94 ALDH1A1 (0.53) ALDH1A1CXCR4SMN1; SMN2KDM4EMAPT
Pyrrolidine SCHEMBL6853053 0.94 ALDH1A1 (0.50) ALDH1A1CXCR4SMN1; SMN2KDM4EMAPT
Pyrrolidine SCHEMBL2219944 0.94
Pyrrolidine SCHEMBL8459727 0.91 ALDH1A1 (0.47) ALDH1A1CXCR4SMN1; SMN2KDM4EMAPT
Pyrrolidine SCHEMBL5823457 0.91 ALDH1A1 (0.47) ALDH1A1CXCR4SMN1; SMN2KDM4EMAPT
Piperidine SCHEMBL9644995 0.88 ALDH1A1 (0.60) ALDH1A1CXCR4SMN1; SMN2KDM4EMAPT
Aziridine SCHEMBL29603143 0.84
Piperidine SCHEMBL8656447 0.82 ALDH1A1 (0.53) ALDH1A1CXCR4SMN1; SMN2KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5147622-A Dithiocarbamic acid derivatives CHEMIE AG BITTERFELD-WOLFEN (DE) 1992-09-15 US disclosed
EP-0150863-B1 SCINTILLATION CONVERTER FOR NEUTRON RADIOGRAPHY SHOWA DENKO KABUSHIKI KAISHA (JP) 1989-05-17 EP disclosed
US-4620939-A Scintillation converter for neutron radiography SHOWA DENKO KABUSHIKI KAISHA (JP) 1986-11-04 US disclosed
US-4557859-A WITH ALUMINUM OR ALUMINUM ALLOY, ELECTROCONDUCTIVE CARBON BLACK, AND SULFUR BASED VULCANIZING AGENT OR SULFUR RELEASING AGENT SHOWA DENKO KABUSHIKI KAISHA (JP) 1985-12-10 US disclosed
EP-0150863-A2 Scintillation converter for neutron radiography SHOWA DENKO KABUSHIKI KAISHA (JP) 1985-08-07 EP disclosed
EP-0103695-A1 Vulcanized olefin-based rubber composition SHOWA DENKO KABUSHIKI KAISHA (JP) 1984-03-28 EP disclosed