Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 7/20 | 0.59 |
| ▸ | MTOR | P42345 | 3/20 | 0.53 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.52 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.52 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.52 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL684055 | 0.90 | KDM1A (0.73) | KDM1AMTORP2RX1P2RX4P2RX7 | |
| SCHEMBL684896 | 0.90 | KDM1A (0.67) | KDM1AMTORNPC1RAB9ANFKB1 | |
| SCHEMBL684581 | 0.86 | KDM1A (0.63) | KDM1AMTORNPC1RAB9ANFKB1 | |
| SCHEMBL9921126 | 0.85 | KDM1A (0.66) | KDM1AMTORP2RX1P2RX4P2RX7 | |
| SCHEMBL685081 | 0.85 | KDM1A (0.62) | KDM1AMTORNPC1RAB9ANFKB1 | |
| SCHEMBL684577 | 0.85 | KDM1A (0.81) | KDM1AMTORNPC1RAB9ANFKB1 | |
| SCHEMBL684021 | 0.83 | MAPT (0.56) | KDM1AMTORP2RX1TMPRSS4NPC1 | |
| SCHEMBL685030 | 0.83 | KDM1A (0.59) | KDM1ANPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL685110 | 0.82 | KDM1A (0.75) | KDM1AMTORNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL686342 | 0.82 | KDM1A (0.57) | KDM1AMTORNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8476194-B2 | Fungicidal compositions including hydrazone derivatives and copper | DOW AGROSCIENCES, LLC (US) | 2013-07-02 | — | — | US | disclosed |
| US-8476194-B2 | Fungicidal compositions including hydrazone derivatives and copper | DOW AGROSCIENCES, LLC (US) | 2013-07-02 | — | — | US | disclosed |
| US-20120021066-A1 | FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | DOW AGROSCIENCES LLC (US) | 2012-01-26 | — | — | US | disclosed |
| US-20120021066-A1 | FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | DOW AGROSCIENCES LLC (US) | 2012-01-26 | — | — | US | disclosed |
| US-20120010075-A1 | SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | DOW AGROSCIENCES LLC (US) | 2012-01-12 | — | — | US | disclosed |
| US-20120010075-A1 | SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | DOW AGROSCIENCES LLC (US) | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010075-A1 | SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | SOD1, CYP51A1, SOD3 | KDM1A 484/4885MTOR 2134/4885P2RX1 2503/4885 |
| US-20120021066-A1 | FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | SOD1, CYP51A1, CYP4Z1 | KDM1A 291/4885MTOR 2360/4885P2RX1 2807/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.