SCHEMBL6853371

SCHEMBL6853371

Cc1cc(O)c(Cl)cc1O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 5/20 0.60
TSHR P16473 4/20 0.60
HPGD P15428 3/20 0.60
ALDH1A1 P00352 5/20 0.55
CYP3A4 P08684 4/20 0.55
ALOX15 P16050 2/20 0.55
MAPT P10636 2/20 0.55
KDM4E B2RXH2 2/20 0.55
CYP1A2 P05177 1/20 0.55
CYP2D6 P10635 1/20 0.55
G6PD P11413 1/20 0.55
CYP2C9 P11712 1/20 0.55
PKM P14618 1/20 0.55
ALOX12 P18054 1/20 0.55
MAPK1 P28482 1/20 0.55
CYP2C19 P33261 1/20 0.55
CCR6 P51684 1/20 0.55
HIF1A Q16665 1/20 0.55
NPSR1 Q6W5P4 1/20 0.55
LMNA P02545 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13855825 0.89 HSD17B10 (0.52) HSD17B10TSHRHPGDALDH1A1CYP3A4
SCHEMBL738726 0.86 HSD17B10 (0.55) HSD17B10TSHRHPGDALDH1A1CYP3A4
SCHEMBL8351711 0.86 HSD17B10 (0.55) HSD17B10TSHRHPGDALDH1A1CYP3A4
SCHEMBL4853924 0.83 HSD17B10 (0.60) HSD17B10TSHRHPGDALDH1A1CYP3A4
SCHEMBL4062679 0.83 LMNA (0.58) HSD17B10TSHRHPGDALDH1A1CYP3A4
SCHEMBL6841859 0.83 LMNA (0.52) HSD17B10TSHRHPGDALDH1A1CYP3A4
SCHEMBL8459523 0.83 TSHR (0.60) HSD17B10TSHRHPGDALDH1A1CYP3A4
SCHEMBL48305 0.82 HSD17B10 (0.86) HSD17B10TSHRHPGDALDH1A1CYP3A4
SCHEMBL70123 0.82 MAPT (0.75) HSD17B10TSHRHPGDALDH1A1CYP3A4
SCHEMBL2662863 0.80 LMNA (0.60) HSD17B10TSHRHPGDALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11760762-B2 Thienopyranones and furanopyranones as kinase, bromodomain, and checkpoint inhibitors SIGNALRX PHARMACEUTICALS, INC. (US) 2023-09-19 US disclosed
US-8481252-B2 Silver halide photographic photosensitive material and production method thereof FUJIFILM CORPORATION (JP) 2013-07-09 US disclosed
US-8383331-B2 Silver halide photographic light-sensitive material for movie FUJIFILM CORPORATION (JP) 2013-02-26 US disclosed
US-8383331-B2 Silver halide photographic light-sensitive material for movie FUJIFILM CORPORATION (JP) 2013-02-26 US disclosed
US-20110275021-A1 SILVER HALIDE PHOTOGRAPHIC LIGHT-SENSITIVE MATERIAL FOR MOVIE FUJIFILM CORPORATION (JP) 2011-11-10 US disclosed
US-20110275021-A1 SILVER HALIDE PHOTOGRAPHIC LIGHT-SENSITIVE MATERIAL FOR MOVIE FUJIFILM CORPORATION (JP) 2011-11-10 US disclosed
US-7919219-B2 Electrophotographic photosensitive body HODOGAYA CHEMICAL CO., LTD. (JP) 2011-04-05 US disclosed
US-7914977-B2 Transparent support, yellow-, cyan-, and magenta-color-forming photosensitive silver halide emulsion layers, and layer containing coupler; cinematography FUJIFILM CORPORATION (JP) 2011-03-29 US disclosed
US-7914977-B2 Transparent support, yellow-, cyan-, and magenta-color-forming photosensitive silver halide emulsion layers, and layer containing coupler; cinematography FUJIFILM CORPORATION (JP) 2011-03-29 US disclosed
US-20100143838-A1 SILVER HALIDE PHOTOGRAPHIC PHOTOSENSITIVE MATERIAL AND PRODUCTION METHOD THEREOF FUJIFILM CORPORATION (JP) 2010-06-10 US disclosed
US-7175976-B2 Silver halide photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 2007-02-13 US disclosed
EP-1024402-B1 Silver halide photographic light-sensitive material and image forming method FUJI PHOTO FILM CO LTD (JP) 2007-01-24 EP disclosed
US-7166422-B2 Silver halide color photographic material, and method of image formation FUJI PHOTO FILM CO., LTD. (JP) 2007-01-23 US disclosed
US-7166422-B2 Silver halide color photographic material, and method of image formation FUJI PHOTO FILM CO., LTD. (JP) 2007-01-23 US disclosed
US-6777148-B2 CHARGE-TRANSPORTING MATERIAL IN A PHOTOSENSITIVE LAYER OF AN ELECTROPHOTOGRAPHIC PHOTORECEPTOR OR USABLE IN VARIOUS DISPLAY DEVICES, AND AN ELECTROPHOTOGRAPHIC PHOTORECEPTOR WHICH USES THE ABOVE ORGANIC PHOTOCONDUCTIVE MATERIAL IN A MITSUBISHI PAPER MILLS LIMITED (JP) 2004-08-17 US disclosed
US-20030148201-A1 Organic photoconductive material and electrophotographic photoreceptor using the material HODOGAYA CHEMICAL CO., LTD. (JP) 2003-08-07 US disclosed
US-4766256-A USING 2-CHLORO-S-HYDROCARBYL HYDROQUINONE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1988-08-23 US disclosed
EP-0262900-A2 Anisotropic melt polyesters with improved glass transition temperature E.I. DU PONT DE NEMOURS AND COMPANY (US) 1988-04-06 EP disclosed
EP-0254682-A1 Phenoxyaliphatylphenylenoxyalkylesters and -amides CIBA-GEIGY AG (CH) 1988-01-27 EP disclosed
US-4719280-A HYDROQUINONES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1988-01-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11760762-B2 Thienopyranones and furanopyranones as kinase, bromodomain, and checkpoint inhibitors CDK1, CDKN1A, CDKL1 HSD17B10 2529/4885TSHR 2452/4885HPGD 2967/4885
US-20030148201-A1 Organic photoconductive material and electrophotographic photoreceptor using the material ALDH1A2, NR2E3, PDE6C HSD17B10 3098/4885TSHR 4758/4885HPGD 696/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.