Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10917121 | 1.00 | ALDH1A1 (0.56) | ALDH1A1KDM4EHTTTP53GAA | |
| SCHEMBL1356508 | 0.81 | ALDH1A1 (0.54) | ALDH1A1KDM4ETP53GAAPOLB | |
| SCHEMBL1356510 | 0.81 | ALDH1A1 (0.54) | ALDH1A1KDM4ETP53GAAPOLB | |
| SCHEMBL9365794 | 0.78 | ALDH1A1 (0.46) | ALDH1A1KDM4EHTTTP53GAA | |
| SCHEMBL9403764 | 0.77 | HSD17B10 (0.61) | ALDH1A1KDM4EHTTTP53TSHR | |
| SCHEMBL4170765 | 0.76 | ALDH1A1 (0.73) | ALDH1A1HTTTP53GAATSHR | |
| SCHEMBL13915547 | 0.76 | ALDH1A1 (0.73) | ALDH1A1HTTTP53GAATSHR | |
| SCHEMBL4170764 | 0.76 | ALDH1A1 (0.73) | ALDH1A1HTTTP53GAATSHR | |
| SCHEMBL1878484 | 0.75 | SMN1; SMN2 (0.53) | L3MBTL1LMNASMN1; SMN2MAPT | |
| SCHEMBL30929593 | 0.75 | SMN1; SMN2 (0.53) | L3MBTL1LMNASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6784293-B1 | SOLUTION AND SOLID-PHASE SYNTHESIS OF BOC-PROTECTED 3-AMINOHYDANTOINS/THIOHYDANTOINS AND 3-AMINODIHYDROURACILS/ DIHYDROTHIOURACILS | THE PROCTER & GAMBLE COMPANY | 2004-08-31 | — | — | US | disclosed |
| WO-2001027087-A2 | PROCESS FOR MAKING BOC-PROTECTED 3-AMINOHYDANTOINS/THIOHYDANTOINS AND 3-AMINODIHYDROURACILS/DIHYDROTHIOURACILS | THE PROCTER & GAMBLE COMPANY (US) | 2001-04-19 | — | — | WO | disclosed |