Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1356510 | 1.00 | ALDH1A1 (0.54) | ALDH1A1TP53KDM4EPOLBHPGD | |
| SCHEMBL6853606 | 0.81 | ALDH1A1 (0.56) | ALDH1A1TP53KDM4EPOLBHPGD | |
| SCHEMBL10917121 | 0.81 | ALDH1A1 (0.56) | ALDH1A1TP53KDM4EPOLBHPGD | |
| SCHEMBL6905360 | 0.81 | ALDH1A1 (0.51) | ALDH1A1TP53KDM4EPOLBHPGD | |
| SCHEMBL6905358 | 0.81 | ALDH1A1 (0.51) | ALDH1A1TP53KDM4EPOLBHPGD | |
| SCHEMBL8795665 | 0.79 | ALDH1A1 (0.49) | ALDH1A1TP53KDM4EPOLBHPGD | |
| SCHEMBL4677601 | 0.78 | TDP1 (0.50) | ALDH1A1POLBHPGDATMTDP1 | |
| SCHEMBL105281 | 0.78 | MAPT (0.51) | ALDH1A1TP53KDM4EPOLBHPGD | |
| SCHEMBL6945061 | 0.78 | L3MBTL1 (0.62) | ALDH1A1KDM4EPOLBHPGDTDP1 | |
| SCHEMBL12172822 | 0.78 | HPGD (0.56) | ALDH1A1TP53POLBHPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130012685-A1 | NOVEL PEPTIDES THAT BIND TO THE ERYTHROPOIETIN RECEPTOR | AFFYMAX, INC. (US) | 2013-01-10 | — | — | US | disclosed |
| US-20120157660-A1 | NOVEL PEPTIDES THAT BIND TO THE ERYTHROPOIETIN RECEPTOR | AFFYMAX, INC. (US) | 2012-06-21 | — | — | US | disclosed |
| US-20110282029-A1 | NOVEL PEPTIDES THAT BIND TO THE ERYTHROPOIETIN RECEPTOR | AFFYMAX, INC. (US) | 2011-11-17 | — | — | US | disclosed |
| US-20090005292-A1 | Novel Peptides that Bind to the Erythropoietin Receptor | AFFYMAX, INC. (US) | 2009-01-01 | — | — | US | disclosed |
| US-20080108564-A1 | NOVEL PEPTIDES THAT BIND TO THE ERYTHROPOIETIN RECEPTOR | AFFYMAX, INC. (US) | 2008-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130012685-A1 | NOVEL PEPTIDES THAT BIND TO THE ERYTHROPOIETIN RECEPTOR | EPOR, PROKR1, EDNRB | ALDH1A1 4119/4885TP53 2568/4885KDM4E 4304/4885 |
| US-20080108564-A1 | NOVEL PEPTIDES THAT BIND TO THE ERYTHROPOIETIN RECEPTOR | EPOR, PROKR1, EDNRB | ALDH1A1 4119/4885TP53 2568/4885KDM4E 4304/4885 |
| US-20110282029-A1 | NOVEL PEPTIDES THAT BIND TO THE ERYTHROPOIETIN RECEPTOR | EPOR, PROKR1, EDNRB | ALDH1A1 4119/4885TP53 2568/4885KDM4E 4304/4885 |
| US-20090005292-A1 | Novel Peptides that Bind to the Erythropoietin Receptor | EPOR, PROKR1, EDNRB | ALDH1A1 4119/4885TP53 2568/4885KDM4E 4304/4885 |
| US-20120157660-A1 | NOVEL PEPTIDES THAT BIND TO THE ERYTHROPOIETIN RECEPTOR | EPOR, PROKR1, EDNRB | ALDH1A1 4119/4885TP53 2568/4885KDM4E 4304/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.