Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.73 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13915547 | 1.00 | ALDH1A1 (0.73) | ALDH1A1GAATDP1HTTHPGD | |
| SCHEMBL4170764 | 1.00 | ALDH1A1 (0.73) | ALDH1A1GAATDP1HTTHPGD | |
| SCHEMBL4166663 | 0.77 | TRPM8 (0.55) | ALDH1A1HTTPOLBL3MBTL1MAPT | |
| SCHEMBL13915548 | 0.77 | TRPM8 (0.55) | ALDH1A1HTTPOLBL3MBTL1MAPT | |
| SCHEMBL4170192 | 0.77 | TRPM8 (0.55) | ALDH1A1HTTPOLBL3MBTL1MAPT | |
| SCHEMBL6853606 | 0.76 | ALDH1A1 (0.56) | ALDH1A1GAATDP1HTTHPGD | |
| SCHEMBL10917121 | 0.76 | ALDH1A1 (0.56) | ALDH1A1GAATDP1HTTHPGD | |
| SCHEMBL23877938 | 0.73 | MAPT (0.47) | ALDH1A1GAATDP1HTTHPGD | |
| SCHEMBL29788435 | 0.72 | ALDH1A1 (0.53) | ALDH1A1GAAHTTPOLBMAPT | |
| SCHEMBL27870684 | 0.72 | ALDH1A1 (0.52) | ALDH1A1GAATDP1HTTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8552208-B2 | Analogs of tetramic acid | University of Tennesseee Research Foundation (US) | 2013-10-08 | — | — | US | disclosed |
| US-20090069406-A1 | Analogs of tetramic acid | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069406-A1 | Analogs of tetramic acid | TFRC, SLC7A1, FTH1 | ALDH1A1 2743/4885GAA 290/4885TDP1 3134/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.