Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | CASP1 | P29466 | 2/20 | 0.34 |
| ▸ | CASP7 | P55210 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | KDM5A | P29375 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6855527 | 0.92 | GAA (0.38) | NOTUMADRB3TMEM97HRH3ALDH1A1 | |
| SCHEMBL6854964 | 0.89 | NOTUM (0.40) | NOTUMADRB3TMEM97HRH3KDM4E | |
| SCHEMBL6855762 | 0.88 | MAPT (0.37) | NOTUMKDM4ESMN1; SMN2TDP1MAPT | |
| SCHEMBL6855298 | 0.80 | NPSR1 (0.39) | KDM4EALDH1A1GAAMAPK1HSD17B10 | |
| SCHEMBL12410700 | 0.79 | NOTUM (0.46) | NOTUMADRB3TMEM97HRH3KDM4E | |
| SCHEMBL6853568 | 0.78 | NOTUM (0.41) | NOTUMADRB3TMEM97HRH3ALDH1A1 | |
| SCHEMBL6849824 | 0.77 | MAPT (0.39) | KDM4EALDH1A1SMN1; SMN2TDP1MAPT | |
| SCHEMBL6857956 | 0.75 | NOTUM (0.39) | NOTUMADRB3TMEM97HRH3KDM4E | |
| SCHEMBL6855538 | 0.74 | MAPT (0.37) | KDM4EALDH1A1SMN1; SMN2TDP1MAPT | |
| SCHEMBL24267919 | 0.70 | MAPK1 (0.51) | NOTUMALDH1A1MAPK1SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6831177-B1 | Preparation of their intermediates, 2-acyl-5-benzylfuran derivatives and 1,2,4-triazole-3- carboxylic acid ester derivatives | SHIONOGI & CO., LTD. (JP) | 2004-12-14 | — | — | US | disclosed |
| EP-1186599-A1 | NOVEL PROCESSES FOR THE PREPARATION OF SUBSTITUTED PROPENONE DERIVATIVES | SHIONOGI & CO., LTD. (JP) | 2002-03-13 | — | — | EP | disclosed |