Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KDM5A | P29375 | 1/20 | 0.30 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.30 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.30 |
| ▸ | STAT5B | P51692 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6853833 | 0.89 | NOTUM (0.39) | NOTUMADRB3TMEM97HRH3CYP4F2 | |
| SCHEMBL6849824 | 0.88 | MAPT (0.39) | MAPTKDM4EPOLBTDP1L3MBTL1 | |
| SCHEMBL6855527 | 0.86 | GAA (0.38) | NOTUMADRB3TMEM97HRH3MAPT | |
| SCHEMBL11851306 | 0.84 | LMNA (0.35) | TMEM97SMN1; SMN2 | |
| SCHEMBL12410700 | 0.81 | NOTUM (0.46) | NOTUMADRB3TMEM97HRH3CYP4F2 | |
| SCHEMBL6857956 | 0.80 | NOTUM (0.39) | NOTUMADRB3TMEM97HRH3CYP4F2 | |
| SCHEMBL6855762 | 0.79 | MAPT (0.37) | NOTUMMAPTKDM4EPOLBTDP1 | |
| SCHEMBL6855538 | 0.79 | MAPT (0.37) | MAPTKDM4EPOLBTDP1L3MBTL1 | |
| SCHEMBL6853568 | 0.78 | NOTUM (0.41) | NOTUMADRB3TMEM97HRH3CYP4F2 | |
| SCHEMBL22040162 | 0.74 | ADORA1 (0.45) | MAPTKDM4EPOLBTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6831177-B1 | Preparation of their intermediates, 2-acyl-5-benzylfuran derivatives and 1,2,4-triazole-3- carboxylic acid ester derivatives | SHIONOGI & CO., LTD. (JP) | 2004-12-14 | — | — | US | disclosed |
| EP-1186599-A1 | NOVEL PROCESSES FOR THE PREPARATION OF SUBSTITUTED PROPENONE DERIVATIVES | SHIONOGI & CO., LTD. (JP) | 2002-03-13 | — | — | EP | disclosed |