Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
| ▸ | MAP3K5 | Q99683 | 2/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.32 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6854520 | 0.87 | MAPT (0.38) | MEN1KMT2ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL6857956 | 0.87 | NOTUM (0.39) | NOTUMADRB3TMEM97HRH3KMT2A | |
| SCHEMBL12410700 | 0.82 | NOTUM (0.46) | NOTUMADRB3TMEM97HRH3KMT2A | |
| SCHEMBL6853833 | 0.78 | NOTUM (0.39) | NOTUMADRB3TMEM97HRH3SMN1; SMN2 | |
| SCHEMBL6854964 | 0.78 | NOTUM (0.40) | NOTUMADRB3TMEM97HRH3KMT2A | |
| SCHEMBL6855527 | 0.76 | GAA (0.38) | NOTUMADRB3TMEM97HRH3SMN1; SMN2 | |
| SCHEMBL7473914 | 0.75 | KMT2A (0.39) | MEN1KMT2ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL24267919 | 0.74 | MAPK1 (0.51) | NOTUMMEN1KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL31728124 | 0.72 | NOTUM (0.43) | NOTUMADRB3TMEM97HRH3HCAR3 | |
| SCHEMBL11373208 | 0.71 | HCAR3 (0.31) | HRH3HCAR3MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6831177-B1 | Preparation of their intermediates, 2-acyl-5-benzylfuran derivatives and 1,2,4-triazole-3- carboxylic acid ester derivatives | SHIONOGI & CO., LTD. (JP) | 2004-12-14 | — | — | US | disclosed |
| EP-1186599-A1 | NOVEL PROCESSES FOR THE PREPARATION OF SUBSTITUTED PROPENONE DERIVATIVES | SHIONOGI & CO., LTD. (JP) | 2002-03-13 | — | — | EP | disclosed |