Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 10/20 | 0.48 |
| ▸ | SLC6A9 | P48067 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | MTOR | P42345 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | HTR2C | P28335 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | THPO | P40225 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13242453 | 0.87 | SLC6A4 (0.63) | SLC6A4SLC6A9MEN1KMT2ALMNA | |
| SCHEMBL685185 | 0.76 | SLC6A9 (0.46) | SLC6A4SLC6A9SLC6A2HRH3HTR1A | |
| SCHEMBL5015289 | 0.76 | SLC6A4 (0.82) | SLC6A4MEN1KMT2ALMNACYP2D6 | |
| SCHEMBL13107035 | 0.76 | SLC6A4 (0.82) | SLC6A4MEN1KMT2ALMNACYP2D6 | |
| Hydrochloric Acid SCHEMBL4942454 | 0.74 | SLC6A4 (0.79) | SLC6A4MEN1KMT2ALMNACYP2D6 | |
| Hydrochloric Acid SCHEMBL17685574 | 0.74 | SLC6A4 (0.79) | SLC6A4MEN1KMT2ALMNACYP2D6 | |
| Oxalic Acid SCHEMBL16347641 | 0.73 | SLC6A4 (0.71) | SLC6A4MEN1KMT2ALMNACYP2D6 | |
| SCHEMBL12546610 | 0.72 | SLC6A4 (0.66) | SLC6A4MEN1KMT2ALMNACYP2D6 | |
| SCHEMBL14393011 | 0.71 | SLC6A4 (0.63) | SLC6A4SLC6A9MEN1KMT2ALMNA | |
| SCHEMBL13042191 | 0.71 | SLC6A9 (0.54) | SLC6A4SLC6A9MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170007598-A1 | COMPOSITIONS FOR AFFECTING WEIGHT LOSS | WILMINGTON SAVINGS FUND SOCIETY, FSB | 2017-01-12 | — | — | US | disclosed |
| US-20150141452-A1 | COMPOSITIONS FOR AFFECTING WEIGHT LOSS | U.S. BANK NATIONAL ASSOCIATION, AS COLLATERAL AGENT | 2015-05-21 | — | — | US | disclosed |
| US-20120010232-A1 | COMPOSITIONS FOR AFFECTING WEIGHT LOSS | OREXIGEN THERAPEUTICS, INC. (US) | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150141452-A1 | COMPOSITIONS FOR AFFECTING WEIGHT LOSS | MC4R, MC3R, MC5R | SLC6A4 978/4885SLC6A9 4130/4885MEN1 1633/4885 |
| US-20170007598-A1 | COMPOSITIONS FOR AFFECTING WEIGHT LOSS | MC4R, MC3R, MC5R | SLC6A4 978/4885SLC6A9 4130/4885MEN1 1633/4885 |
| US-20120010232-A1 | COMPOSITIONS FOR AFFECTING WEIGHT LOSS | MC4R, MC3R, MC5R | SLC6A4 978/4885SLC6A9 4130/4885MEN1 1633/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.