Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 3/20 | 0.44 |
| ▸ | DPP4 | P27487 | 2/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3061093 | 1.00 | SCN4A (0.44) | SCN4ADPP4F2GRIN2DGRIN3B | |
| SCHEMBL5455701 | 1.00 | SCN4A (0.44) | SCN4ADPP4F2GRIN2DGRIN3B | |
| SCHEMBL10349212 | 0.92 | METAP2 (0.43) | SCN4ADPP4IDO1 | |
| SCHEMBL28672429 | 0.90 | METAP2 (0.46) | SCN4AIDO1 | |
| SCHEMBL12927229 | 0.90 | METAP2 (0.46) | SCN4AIDO1 | |
| SCHEMBL9009370 | 0.90 | METAP2 (0.46) | SCN4AIDO1 | |
| SCHEMBL28660567 | 0.90 | METAP2 (0.46) | SCN4AIDO1 | |
| SCHEMBL7898573 | 0.90 | METAP2 (0.46) | SCN4AIDO1 | |
| Hydrochloric Acid SCHEMBL9009360 | 0.88 | IDO1 (0.46) | SCN4AIDO1 | |
| SCHEMBL8494340 | 0.84 | OPRM1 (0.47) | SCN4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011013644-A1 | SUBSTITUTED PIPERIDINE COMPOUND | 第一三共株式会社 (JP) | 2011-02-03 | — | — | WO | disclosed |