SCHEMBL685437

SCHEMBL685437

COc1ccc(Cc2ccc(Oc3ccc(S(=O)(=O)c4ccc(C)cc4)cc3)cc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.61
SMN1; SMN2 Q16637 1/20 0.61
ACHE P22303 2/20 0.60
BCHE P06276 1/20 0.60
PKM P14618 2/20 0.59
ALDH1A1 P00352 3/20 0.56
TDP1 Q9NUW8 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
GAA P10253 2/20 0.51
EGFR P00533 1/20 0.51
CYP3A4 P08684 1/20 0.51
CYP2C9 P11712 1/20 0.51
CYP2C19 P33261 1/20 0.51
RAPGEF4 Q8WZA2 1/20 0.50
MMP2 P08253 2/20 0.49
MMP9 P14780 2/20 0.49
MMP8 P22894 2/20 0.49
MMP12 P39900 2/20 0.49
MMP13 P45452 2/20 0.49
MMP14 P50281 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15144016 1.00 HTT (0.61) HTTSMN1; SMN2ACHEBCHEPKM
SCHEMBL13291969 1.00 HTT (0.61) HTTSMN1; SMN2ACHEBCHEPKM
SCHEMBL13059601 1.00 HTT (0.61) HTTSMN1; SMN2ACHEBCHEPKM
SCHEMBL13249145 0.96 HTT (0.56) HTTSMN1; SMN2ACHEBCHEPKM
SCHEMBL13910296 0.96 HTT (0.56) HTTSMN1; SMN2ACHEBCHEPKM
SCHEMBL13508239 0.96 HTT (0.56) HTTSMN1; SMN2ACHEBCHEPKM
SCHEMBL16281208 0.94 PKM (0.68) HTTSMN1; SMN2ACHEBCHEPKM
SCHEMBL822854 0.94 HTT (0.69) HTTSMN1; SMN2ACHEBCHEPKM
SCHEMBL13059602 0.94 PKM (0.68) HTTSMN1; SMN2ACHEBCHEPKM
SCHEMBL13321724 0.94 HTT (0.69) HTTSMN1; SMN2ACHEBCHEPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11872532-B2 Ultrafiltration membranes for dairy protein separation Campbell Membrane Technologies, Inc. (US) 2024-01-16 US disclosed
US-9722270-B2 Polymer, electrolyte membrane and electrode for a fuel cell, each including the polymer, fuel cell including at least one of the electrolyte membrane, and the electrode SAMSUNG ELECTRONICS CO., LTD. (KR) 2017-08-01 US disclosed
US-9035287-B2 Polymeric materials for use in metal-oxide-semiconductor field-effect transistors POLYERA CORPORATION (US) 2015-05-19 US disclosed
US-20150037708-A1 POLYMER, ELECTROLYTE MEMBRANE AND ELECTRODE FOR A FUEL CELL, EACH INCLUDING THE POLYMER, FUEL CELL INCLUDING AT LEAST ONE OF THE ELECTROLYTE MEMBRANE, AND THE ELECTRODE SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-02-05 US disclosed
US-20140262183-A1 POLYMER TUBE HEAT EXCHANGER CARRIER CORPORATION 2014-09-18 US disclosed
US-20140217395-A1 Polymeric Materials for Use in Metal-Oxide-Semiconductor Field-Effect Transistors POLYERA CORPORATION (US) 2014-08-07 US disclosed
US-8334358-B2 Sulfonated poly(arylene ether) copolymers and related polymer electrolyte membranes and fuel cells HYUNDAI MOTOR COMPANY (KR) 2012-12-18 US disclosed
US-8268195-B2 Electrically conductive films formed from dispersions comprising polythiophenes and ether containing polymers AIR PRODUCTS AND CHEMICALS, INC. (US) 2012-09-18 US disclosed
US-8178590-B2 Block copolymer and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-05-15 US disclosed
US-20110060093-A1 Fire resistant, high flow poly(aryl ether sulfone) composition SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2011-03-10 US disclosed
US-7740942-B2 Opto-electronic devices containing sulfonated copolymers GENERAL ELECTRIC COMPANY (US) 2010-06-22 US disclosed
US-20100081007-A1 Electrically Conductive Films Formed From Dispersions Comprising Polythiophenes and Ether Containing Polymers AIR PRODUCTS AND CHEMICALS, INC. (US) 2010-04-01 US disclosed
US-7651802-B2 proton conductive membrane and electrode layers comprising the polymer electrolyte which is an aromatic polyether copolymer containing firast monomer with sulfonic acid group and second monomer without protonic acid group; used for example in fuel cells, water electrolysis, gas or humidity sensor JSR CORPORATION (JP) 2010-01-26 US disclosed
US-20080145669-A1 OPTO-ELECTRONIC DEVICES CONTAINING SULFONATED COPOLYMERS GENERAL ELECTRIC COMPANY (US) 2008-06-19 US disclosed
US-20080004443-A1 Sulfonated polyaryletherketone-block-polyethersulfone copolymers GENERAL ELECTRIC COMPANY 2008-01-03 US disclosed
US-20070281195-A1 Block copolymer and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED 2007-12-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080004443-A1 Sulfonated polyaryletherketone-block-polyethersulfone copolymers ABCB7, AKR1B10, RER1 HTT 2491/4885SMN1; SMN2 1607/4885ACHE 4884/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.