Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 8/20 | 0.43 |
| ▸ | THRA | P10827 | 7/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7592718 | 0.84 | SOS1 (0.47) | THRBTHRAMEN1KMT2AL3MBTL1 | |
| SCHEMBL4961754 | 0.84 | GAA (0.41) | THRBTHRACNR1MEN1KMT2A | |
| SCHEMBL6853009 | 0.84 | THRA (0.45) | THRBTHRA | |
| SCHEMBL6861552 | 0.83 | THRB (0.40) | THRBTHRACNR1MEN1KMT2A | |
| SCHEMBL6861254 | 0.83 | THRA (0.45) | THRBTHRACNR1L3MBTL1ALDH1A1 | |
| SCHEMBL6854274 | 0.83 | PPARA (0.41) | THRBTHRAMEN1KMT2AL3MBTL1 | |
| SCHEMBL6852992 | 0.83 | THRA (0.57) | THRBTHRAMEN1KMT2AALDH1A1 | |
| SCHEMBL1642407 | 0.82 | THRA (0.58) | THRBTHRA | |
| SCHEMBL6515875 | 0.82 | SMN1; SMN2 (0.53) | THRBTHRAMEN1KMT2AGAA | |
| SCHEMBL1640506 | 0.82 | THRA (0.48) | THRBTHRACNR1L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6777442-B2 | Diphenyl derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2004-08-17 | — | — | US | disclosed |
| US-20030105078-A1 | Diphenyl derivatives | BAYER AKTIENGESSELLSCHAFT (DE) | 2003-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030105078-A1 | Diphenyl derivatives | DPP4, DPP3, DPM1 | THRB 4614/4885THRA 4665/4885CNR1 1229/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.