Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 17/20 | 0.45 |
| ▸ | THRB | P10828 | 17/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | PCNA | P12004 | 1/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | RXRA | P19793 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6852992 | 0.88 | THRA (0.57) | THRATHRBPOLB | |
| SCHEMBL6854363 | 0.87 | THRB (0.58) | THRATHRB | |
| SCHEMBL6852998 | 0.87 | THRB (0.57) | THRATHRB | |
| SCHEMBL6849370 | 0.85 | THRB (0.49) | THRATHRBABCB11LMNACYP1A2 | |
| SCHEMBL6854843 | 0.85 | THRA (0.41) | THRATHRB | |
| SCHEMBL6854527 | 0.85 | THRA (0.45) | THRATHRBMMP1MMP2MMP3 | |
| SCHEMBL6854726 | 0.84 | THRB (0.43) | THRATHRB | |
| SCHEMBL6738420 | 0.84 | THRA (0.44) | THRATHRBSMN1; SMN2MMP2MMP9 | |
| SCHEMBL1642319 | 0.84 | THRA (0.59) | THRATHRB | |
| SCHEMBL14489255 | 0.83 | THRB (0.51) | THRATHRBMMP1MMP2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6777442-B2 | Diphenyl derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2004-08-17 | — | — | US | disclosed |
| US-20030105078-A1 | Diphenyl derivatives | BAYER AKTIENGESSELLSCHAFT (DE) | 2003-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030105078-A1 | Diphenyl derivatives | DPP4, DPP3, DPM1 | THRA 4665/4885THRB 4614/4885ABCB11 778/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.