Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6078877 | 0.92 | ENPP2 (0.41) | ALDH1A1SMN1; SMN2HTTLMNAL3MBTL1 | |
| SCHEMBL6078643 | 0.89 | F10 (0.41) | ALDH1A1SMN1; SMN2MEN1KMT2AHTT | |
| SCHEMBL6078359 | 0.87 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2MEN1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL6079263 | 0.87 | F10 (0.40) | ALDH1A1KMT2AHTTLMNAL3MBTL1 | |
| SCHEMBL6079252 | 0.86 | F10 (0.56) | F10POLB | |
| SCHEMBL6079274 | 0.85 | F10 (0.47) | ALDH1A1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL6078462 | 0.84 | F10 (0.40) | ALDH1A1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL6079539 | 0.81 | ENPP2 (0.43) | ALDH1A1SMN1; SMN2MEN1KMT2AHTT | |
| SCHEMBL6078661 | 0.81 | ATXN2 (0.41) | ALDH1A1SMN1; SMN2HTTLMNAF10 | |
| SCHEMBL6079290 | 0.81 | ENPP2 (0.42) | ALDH1A1SMN1; SMN2MEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1191028-B1 | TRICYCLIC COMPOUNDS HAVING SPIRO UNION | MOCHIDA PHARM CO LTD (JP) | 2004-11-03 | — | — | EP | disclosed |