Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | UBE2N | P61088 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4577239 | 0.76 | MCL1 (0.41) | MAPTKDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL6855931 | 0.76 | NQO1 (0.31) | SMN1; SMN2 | |
| SCHEMBL6849922 | 0.71 | MAPT (0.53) | MAPTKDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL6858030 | 0.69 | CYP3A4 (0.33) | MEN1CYP3A4PTGS1DRD3KMT2A | |
| SCHEMBL9686058 | 0.67 | ALDH1A1 (0.46) | MAPTKDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL3062337 | 0.67 | GAA (0.39) | MAPTKDM4EUBE2NHSD17B10MEN1 | |
| SCHEMBL27272020 | 0.66 | KMT2A (0.38) | MAPTKDM4EHSD17B10MEN1CYP3A4 | |
| SCHEMBL6856079 | 0.66 | CHRNA4 (0.47) | MAPTKDM4EMEN1KMT2AL3MBTL1 | |
| SCHEMBL8613357 | 0.65 | MAPT (0.45) | MAPTHSD17B10KMT2AL3MBTL1SMN1; SMN2 | |
| SCHEMBL19919916 | 0.65 | CYP19A1 (0.33) | MAPTKDM4EUBE2NHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6831177-B1 | Preparation of their intermediates, 2-acyl-5-benzylfuran derivatives and 1,2,4-triazole-3- carboxylic acid ester derivatives | SHIONOGI & CO., LTD. (JP) | 2004-12-14 | — | — | US | disclosed |
| EP-1186599-A1 | NOVEL PROCESSES FOR THE PREPARATION OF SUBSTITUTED PROPENONE DERIVATIVES | SHIONOGI & CO., LTD. (JP) | 2002-03-13 | — | — | EP | disclosed |