SCHEMBL9686058

SCHEMBL9686058

Cc1coc(C(=O)c2ccccc2)c1C

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.46
NPC1 O15118 4/20 0.45
RAB9A P51151 3/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
CES2 O00748 5/20 0.42
CES1 P23141 5/20 0.42
KMT2A Q03164 3/20 0.41
MEN1 O00255 2/20 0.41
KDM4E B2RXH2 1/20 0.41
MAPT P10636 2/20 0.41
LMNA P02545 1/20 0.41
ATM Q13315 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
SRD5A2 P31213 1/20 0.41
HTT P42858 1/20 0.39
HPGD P15428 1/20 0.39
TSHR P16473 1/20 0.39
AKR1C3 P42330 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1667006 0.72 KMT2A (0.49) ALDH1A1NPC1RAB9AL3MBTL1KMT2A
SCHEMBL10349890 0.72 ALDH1A1 (0.48) ALDH1A1NPC1RAB9AL3MBTL1KMT2A
Benzophenone SCHEMBL2156249 0.71 ALDH1A1 (0.74) ALDH1A1NPC1RAB9AL3MBTL1CES2
SCHEMBL1044178 0.69 ALDH1A1 (0.55) ALDH1A1NPC1RAB9AL3MBTL1KMT2A
SCHEMBL1666686 0.69 ALDH1A1 (0.62) ALDH1A1NPC1RAB9AL3MBTL1CES2
SCHEMBL5169856 0.69 ALDH1A1 (0.62) ALDH1A1NPC1RAB9AL3MBTL1CES2
SCHEMBL9323609 0.68 ALDH1A1 (0.61) ALDH1A1NPC1RAB9AL3MBTL1CES2
Benzophenone SCHEMBL7454682 0.67 ALDH1A1 (0.88) ALDH1A1NPC1RAB9AL3MBTL1CES2
SCHEMBL3039645 0.67 ALDH1A1 (0.59) ALDH1A1NPC1RAB9AL3MBTL1CES2
SCHEMBL10007412 0.67 ALDH1A1 (0.59) ALDH1A1L3MBTL1KMT2AMEN1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0494567-A1 Reagent and three phase hydrocarbonylation process RHONE-POULENC CHIMIE (FR) 1992-07-15 EP disclosed