Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | EDNRA | P25101 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8869893 | 0.85 | MCL1 (0.38) | MCL1MEN1KMT2AGPR35SMN1; SMN2 | |
| SCHEMBL6855931 | 0.81 | NQO1 (0.31) | SMN1; SMN2 | |
| SCHEMBL4611852 | 0.79 | MKNK2 (0.36) | SMN1; SMN2KDM4EPOLBTDP1ALOX15 | |
| SCHEMBL30885082 | 0.79 | GPR35 (0.44) | MCL1MEN1KMT2AGPR35SMN1; SMN2 | |
| SCHEMBL2866739 | 0.79 | CYP1A2 (0.42) | MCL1MEN1KMT2ANOTUMGPR35 | |
| SCHEMBL6854948 | 0.76 | MAPT (0.34) | MEN1KMT2ASMN1; SMN2KDM4EL3MBTL1 | |
| SCHEMBL9686058 | 0.76 | ALDH1A1 (0.46) | MEN1KMT2AKDM4EL3MBTL1HPGD | |
| Cyclopropane SCHEMBL11657479 | 0.74 | CYP1A2 (0.38) | MCL1MEN1KMT2ANOTUMSMN1; SMN2 | |
| SCHEMBL11468226 | 0.71 | TDP1 (0.39) | MEN1KMT2AKDM4EL3MBTL1POLB | |
| SCHEMBL6766747 | 0.68 | PKM (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104693355-B | Terminal-modified conjugated diene-vinyl aromatic hydrocarbon copolymer and synthesis method thereof | 奇美实业股份有限公司 | 2017-08-04 | — | — | CN | claimed |
| WO-2024259171-A9 | KEAP1 INHIBITORS AND USES THEREOF | VIVIDION THERAPEUTICS, INC. (US) | 2025-01-23 | — | — | WO | disclosed |
| US-20250011291-A1 | KEAP1 INHIBITORS AND USES THEREOF | VIVIDION THERAPEUTICS, INC. | 2025-01-09 | — | — | US | disclosed |
| WO-2024259171-A2 | KEAP1 INHIBITORS AND USES THEREOF | VIVIDION THERAPEUTICS, INC. (US) | 2024-12-19 | — | — | WO | disclosed |
| CN-113214465-A | Poly (ethylene furan acid ester) copolymer and method | 可口可乐公司 | 2021-08-06 | — | — | CN | disclosed |
| EP-3143068-B1 | THERMOPLASTIC AROMATIC POLYESTERS COMPRISING TETRAHYDROFURAN-DIMETHANOL AND FURANDICARBOXYLIC ACID MOTIFS | ROQUETTE FRERES (FR) | 2018-05-02 | — | — | EP | disclosed |
| EP-3143068-A1 | THERMOPLASTIC AROMATIC POLYESTERS COMPRISING TETRAHYDROFURAN-DIMETHANOL AND FURANDICARBOXYLIC ACID MOTIFS | Roquette Frères (FR) | 2017-03-22 | — | — | EP | disclosed |
| WO-2015170050-A1 | THERMOPLASTIC AROMATIC POLYESTERS COMPRISING TETRAHYDROFURAN-DIMETHANOL AND FURANDICARBOXYLIC ACID MOTIFS | ROQUETTE FRERES (FR) | 2015-11-12 | — | — | WO | disclosed |
| CN-101115711-A | Diacylglycerol acyltransferase inhibitors | HOFFMANN LA ROCHE (CH) | 2008-01-30 | — | — | CN | disclosed |
| US-7317125-B2 | Diacylglycerol acyltransferase inhibitors | HOFFMAN-LA ROCHE INC. (US) | 2008-01-08 | — | — | US | disclosed |
| EP-1848687-A1 | INHIBITORS OF DIACYLGLYCEROL ACYLTRANSFERASE (DGAT) | F. Hoffmann-Roche AG (CH) | 2007-10-31 | — | — | EP | disclosed |
| WO-2007001335-A2 | RAMOPLANIN DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | VICURON PHARMACEUTICALS INC. (US) | 2007-01-04 | — | — | WO | disclosed |
| US-20060178532-A1 | Diacylglycerol acyltransferase inhibitors | VIA PHARMACEUTICALS, INC. | 2006-08-10 | — | — | US | disclosed |
| WO-2006082010-A1 | INHIBITORS OF DIACYLGLYCEROL ACYLTRANSFERASE (DGAT) | F.HOFFMANN-LA ROCHE AG (CH) | 2006-08-10 | — | — | WO | disclosed |
| US-4303548-A | Process for coating dispersed minute droplets with membrane | MITSUBISHI PAPER MILLS, LTD. (JP) | 1981-12-01 | — | — | US | disclosed |
| US-4097485-A | HERBICIDES | VELSICOL CHEMICAL CORPORATION (US) | 1978-06-27 | — | — | US | disclosed |
| US-4086241-A | Benzothiazolylimidazolidinone esters of furyl and thienyl substituted acids | VELSICOL CHEMICAL CORPORATION (US) | 1978-04-25 | — | — | US | disclosed |
| US-4061648-A | HERBICIDES | VELSICOL CHEMICAL CORPORATION (US) | 1977-12-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060178532-A1 | Diacylglycerol acyltransferase inhibitors | DGAT2, DGAT1, LCAT | MCL1 3215/4885MEN1 3463/4885KMT2A 1380/4885 |
| US-20250011291-A1 | KEAP1 INHIBITORS AND USES THEREOF | KEAP1, NFE2L2, NQO1 | MCL1 557/4885MEN1 3793/4885KMT2A 1356/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.