Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2860506 | 0.85 | CYP3A4 (0.39) | NPC1RAB9A | |
| SCHEMBL13021621 | 0.83 | — | — | |
| SCHEMBL646184 | 0.79 | KDM4E (0.42) | NPC1RAB9A | |
| SCHEMBL10573288 | 0.75 | — | — | |
| SCHEMBL13302784 | 0.73 | ALDH1A1 (0.39) | — | |
| SCHEMBL7219276 | 0.70 | ALDH1A1 (0.43) | NPC1RAB9A | |
| SCHEMBL8764968 | 0.70 | CNKSR1 (0.31) | — | |
| SCHEMBL9180206 | 0.70 | NPC1 (0.41) | NPC1RAB9A | |
| SCHEMBL688102 | 0.70 | ALDH1A1 (0.40) | — | |
| SCHEMBL11611736 | 0.70 | NPC1 (0.41) | NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6780459-B2 | Method for stabilizing irregular structures | MACPHERSON SCOTT (CA) | 2004-08-24 | — | — | US | disclosed |