Known targets — ChEMBL curated mechanism
BTKCACNA1CCACNA1DCACNA1FCACNA1SCACNA2D1CACNA2D2DRD2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQHRH1HTR2AP2RY12
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NT5E | P21589 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diethylamine SCHEMBL27879398 | 0.90 | SMN1; SMN2 (0.53) | TSHRSMN1; SMN2PSIP1GAAPKM | |
| SCHEMBL27863111 | 0.90 | SMN1; SMN2 (0.53) | TSHRSMN1; SMN2PSIP1GAAPKM | |
| SCHEMBL6938340 | 0.87 | TSHR (0.59) | TSHRSMN1; SMN2PSIP1GAAPKM | |
| SCHEMBL27464245 | 0.86 | TSHR (0.76) | TSHRSMN1; SMN2PSIP1PKMPOLB | |
| Butane SCHEMBL2906063 | 0.86 | TSHR (0.76) | TSHRSMN1; SMN2PSIP1GAAPKM | |
| SCHEMBL4669722 | 0.86 | TSHR (0.76) | TSHRSMN1; SMN2PSIP1PKMPOLB | |
| SCHEMBL3719208 | 0.86 | TSHR (0.76) | TSHRSMN1; SMN2PSIP1PKMPOLB | |
| SCHEMBL27879414 | 0.85 | SMN1; SMN2 (0.48) | TSHRSMN1; SMN2GAAPKMTDP1 | |
| SCHEMBL28799446 | 0.85 | TDP1 (0.51) | TSHRSMN1; SMN2PSIP1GAAPKM | |
| Propane SCHEMBL28882618 | 0.83 | TSHR (0.80) | TSHRSMN1; SMN2PSIP1PKMPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6797146-B2 | CONTACTING WITH AN ELECTROPLATING BATH OF A SOURCE OF METAL IONS, AN ELECTROLYTE COMPRISING TWO OR MORE ACIDS, AND ADDITIVES | SHIPLEY COMPANY, L.L.C. | 2004-09-28 | — | — | US | disclosed |
| US-20020053519-A1 | Seed layer repair | SHIPLEY COMPANY, L.L.C. | 2002-05-09 | — | — | US | disclosed |