Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.31 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30720856 | 0.73 | HPGD (0.32) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL9164742 | 0.71 | ALDH1A1 (0.38) | PDE4APDE4BPDE4CPDE4DAGTR1 | |
| SCHEMBL7270139 | 0.69 | KDM4E (0.46) | ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL7450713 | 0.69 | NPC1 (0.33) | — | |
| SCHEMBL30720877 | 0.69 | AGER (0.36) | — | |
| SCHEMBL725696 | 0.66 | SMN1; SMN2 (0.39) | AGTR1AGTR2LMNAATMSMN1; SMN2 | |
| SCHEMBL27341246 | 0.63 | PDE4A (0.37) | PDE4APDE4BPDE4CPDE4DAGTR1 | |
| SCHEMBL633213 | 0.62 | HRH3 (0.38) | ALDH1A1MAPK1 | |
| SCHEMBL7092724 | 0.62 | KCNH2 (0.56) | — | |
| SCHEMBL20113653 | 0.61 | CCR1 (0.38) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011004384-A2 | PROCESS FOR THE PREPARATION OF EPROSARTAN | GLOCHEM INDUSTRIES LIMITED (IN) | 2011-01-13 | — | — | WO | disclosed |