Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.48 |
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11236258 | 0.94 | POLB (0.50) | MTNR1AMTNR1BELANEKMT2AKDM4E | |
| SCHEMBL218655 | 0.89 | ELANE (0.56) | ELANELMNAKMT2AALDH1A1MEN1 | |
| SCHEMBL10891338 | 0.89 | TP53 (0.50) | ELANELMNAMAPK1L3MBTL1MAPT | |
| SCHEMBL65346 | 0.87 | TDP1 (0.52) | MTNR1AMTNR1BLMNAMAPK1L3MBTL1 | |
| SCHEMBL7924946 | 0.84 | GAA (0.45) | MTNR1AELANELMNAMAPTKMT2A | |
| SCHEMBL26846471 | 0.84 | LMNA (0.59) | ELANELMNAMAPTKMT2AKDM4E | |
| SCHEMBL14173262 | 0.84 | ELANE (0.51) | MTNR1AMTNR1BELANELMNAMAPT | |
| SCHEMBL10204675 | 0.83 | LMNA (0.50) | MTNR1AMTNR1BELANELMNAMAPK1 | |
| SCHEMBL378966 | 0.83 | POLB (0.50) | MTNR1AMTNR1BELANEPOLBAPEX1 | |
| SCHEMBL7186457 | 0.83 | CES2 (0.50) | MTNR1AMTNR1BELANELMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6780899-B2 | ACRYLIC ESTER HOMOPOLYMERS CONTAINING CHEMICAL CROSSLINKERS HAVING THE UNIQUE ABILITY TO PRODUCE STABLE ELASTICITY IN CONJUNCTION WITH OTHER UNIQUE PROPERTIES SUCH AS OPTICAL CLARITY AND HIGH REFRACTIVE INDEX | MEDENNIUM, INC. | 2004-08-24 | — | — | US | claimed |