⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25582070 | 0.83 | GNAI3 (0.56) | — | |
| SCHEMBL6968840 | 0.83 | GNAI3 (0.56) | — | |
| SCHEMBL29893804 | 0.83 | GNAI3 (0.66) | — | |
| SCHEMBL9437364 | 0.80 | — | — | |
| SCHEMBL19018618 | 0.80 | GNAI3 (0.45) | — | |
| SCHEMBL17188946 | 0.79 | CHRNB2 (0.35) | — | |
| SCHEMBL19977457 | 0.79 | GNAI3 (0.35) | — | |
| SCHEMBL5827728 | 0.78 | — | — | |
| SCHEMBL13772115 | 0.77 | GNAO1 (0.70) | — | |
| SCHEMBL11420212 | 0.77 | SAT1 (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210353610-A1 | SMALL MOLECULE MENIN INHIBITORS | SERVIER PHARMACEUTICALS LLC | 2021-11-18 | — | — | US | disclosed |
| WO-2017155765-A1 | BICYCLIC ARYL MONOBACTAM COMPOUNDS AND METHODS OF USE THEREOF FOR THE TREATMENT OF BACTERIAL INFECTIONS | MERCK SHARP & DOHME CORP. (US) | 2017-09-14 | — | — | WO | disclosed |
| WO-2011096461-A1 | QUINOLINE DERIVATIVE | 大正製薬株式会社 (JP) | 2011-08-11 | — | — | WO | disclosed |