Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KISS1R | Q969F8 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 7/20 | 0.36 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.35 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.34 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.34 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.34 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.34 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.34 |
| ▸ | FNTA | P49354 | 1/20 | 0.34 |
| ▸ | FNTB | P49356 | 1/20 | 0.34 |
| ▸ | RRM1 | P23921 | 1/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.31 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL97745 | 0.90 | CPB2 (0.41) | KISS1RFOLH1CPB2KDM4AKDM4C | |
| SCHEMBL546909 | 0.83 | GSR (0.42) | KISS1RFOLH1CPB2GNAI3GNAO1 | |
| SCHEMBL4836560 | 0.78 | SLC1A1 (0.42) | KISS1R | |
| SCHEMBL16326302 | 0.77 | KISS1R (0.36) | KISS1RCPB2KDM4AKDM4C | |
| SCHEMBL25911366 | 0.77 | KISS1R (0.37) | KISS1RUSP2TSHR | |
| SCHEMBL29315304 | 0.77 | USP2 (0.44) | KISS1RDPP7ALDH1A2ALDH1A1ALDH2 | |
| SCHEMBL29313570 | 0.77 | USP2 (0.44) | KISS1RDPP7ALDH1A2ALDH1A1ALDH2 | |
| SCHEMBL24642318 | 0.76 | FOLH1 (0.35) | FOLH1 | |
| SCHEMBL24642323 | 0.76 | FOLH1 (0.35) | FOLH1 | |
| SCHEMBL1697811 | 0.76 | ALOX15 (0.38) | FOLH1DPP7GNAI3GNAO1GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6797808-B1 | FOUND NATURALLY IN VENOM OF THE CONE SNAILS; HAVE SPECIFICITY FOR NEURONAL NICOTINIC ACETYLCHOLINE RECEPTORS; FOR TREATING CARDIOVASCULAR, GASTRIC MOTILITY, AND MOOD DISORDERS, URINARY INCONTINENCE, NICOTINE ADDICTION, AND SMALL CELL LUNG CANCER | UNIVERSITY OF UTAH RESEARCH FOUNDATION | 2004-09-28 | — | — | US | disclosed |