SCHEMBL6856476

SCHEMBL6856476

C=C(C)C(=O)OCC1CSC(c2ccc3ccccc3c2)S1

nearest known ligand 0.35

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.35
ACHE P22303 2/20 0.34
KDM4E B2RXH2 2/20 0.33
NPC1 O15118 1/20 0.33
HTT P42858 1/20 0.33
RAB9A P51151 1/20 0.33
LMNA P02545 1/20 0.32
SLC6A4 P31645 3/20 0.32
SLC6A3 Q01959 3/20 0.32
CTDSP1 Q9GZU7 1/20 0.31
HCAR2 Q8TDS4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5209184 0.95 ALDH1A1 (0.38) ALDH1A1HTT
SCHEMBL5206209 0.87 ALDH1A1 (0.37) ALDH1A1HTT
SCHEMBL5209148 0.87 ALDH1A1 (0.38) ALDH1A1HTT
SCHEMBL5209650 0.87 ALDH1A1 (0.42) ALDH1A1HTT
SCHEMBL7041104 0.86 ALDH1A1 (0.39) ALDH1A1HTT
SCHEMBL6862967 0.84 MMP2 (0.40) ALDH1A1NPC1HTTRAB9A
SCHEMBL6860962 0.84 ALDH1A1 (0.36) ALDH1A1ACHENPC1HTTRAB9A
SCHEMBL6862296 0.83
SCHEMBL6860926 0.83 THRB (0.36) ALDH1A1KDM4ESLC6A4SLC6A3HCAR2
SCHEMBL6860789 0.83 GAA (0.39) ALDH1A1KDM4EHTTRAB9ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6794471-B2 OF A HYDROXYHYDROCARBYL- OR MERCAPTOHYDROCARBYL- DITHIOLANE; CURED OPTICAL ARTICLE FORMED BY PHOTOPOLYMERIZING THE ACRYLATE MITSUI CHEMICALS, INC. (JP) 2004-09-21 US disclosed
EP-1193264-B1 Acrylic ester compound and usage thereof MITSUI CHEMICALS INC (JP) 2004-03-31 EP disclosed
EP-1193264-A1 Acrylic ester compound and usage thereof Mitsui Chemicals, Inc. (JP) 2002-04-03 EP disclosed