Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.54 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.44 |
| ▸ | BRS3 | P32247 | 1/20 | 0.43 |
| ▸ | KDM5A | P29375 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.42 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1697133 | 0.84 | NR4A2 (0.48) | NR4A2DAO | |
| SCHEMBL4017043 | 0.84 | HCAR2 (0.45) | HCAR2KDM5AKDM4CKDM5BPARP1 | |
| SCHEMBL5779014 | 0.83 | PDE3B (0.49) | HCAR2 | |
| SCHEMBL15622305 | 0.74 | AR (0.47) | BRS3KDM5AKDM4CKDM5B | |
| SCHEMBL28105342 | 0.74 | HCAR2 (0.52) | HCAR2NR4A2BRS3SLC1A1 | |
| SCHEMBL22534331 | 0.73 | KDM5B (0.46) | BRS3KDM5AKDM4CKDM5BPARP1 | |
| SCHEMBL9937529 | 0.73 | HCAR2 (0.51) | HCAR2NR4A2BRS3SLC1A1 | |
| SCHEMBL4448337 | 0.73 | BRS3 (0.47) | HCAR2NR4A2BRS3KDM5AKDM4C | |
| SCHEMBL28214966 | 0.72 | DCLRE1B (0.47) | NR4A2 | |
| SCHEMBL28117926 | 0.72 | TSHR (0.57) | HCAR2NR4A2BRS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1444233-A2 | A 2B? ADENOSINE RECEPTOR ANTAGONISTS | CV THERAPEUTICS, INC. (US) | 2004-08-11 | — | — | EP | claimed |
| WO-2003042214-A2 | A2B ADENOSINE RECEPTOR ANTAGONISTS | CV THERAPEUTICS, INC. (US) | 2003-05-22 | — | — | WO | claimed |