Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5B | Q9UGL1 | 4/20 | 0.46 |
| ▸ | KDM5A | P29375 | 1/20 | 0.46 |
| ▸ | KDM6B | O15054 | 4/20 | 0.43 |
| ▸ | KDM4A | O75164 | 3/20 | 0.43 |
| ▸ | KDM4D | Q6B0I6 | 3/20 | 0.43 |
| ▸ | KDM3B | Q7LBC6 | 3/20 | 0.43 |
| ▸ | HIF1AN | Q9NWT6 | 3/20 | 0.43 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.43 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | BRS3 | P32247 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4019423 | 0.90 | KDM6B (0.45) | KDM5BKDM5AKDM6BKDM4AKDM4D | |
| SCHEMBL28742830 | 0.87 | P2RX3 (0.40) | KDM5BKDM5AP2RX3NPC1RAB9A | |
| SCHEMBL4017043 | 0.85 | HCAR2 (0.45) | KDM5BKDM5AKDM6BKDM4AKDM4D | |
| SCHEMBL20768106 | 0.82 | MMP2 (0.42) | P2RX3NPC1RAB9A | |
| SCHEMBL716631 | 0.82 | TSHR (0.50) | P2RX3NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL7506599 | 0.81 | TSHR (0.47) | KDM5BKDM6BKDM4AKDM4DHIF1AN | |
| SCHEMBL971141 | 0.77 | HCAR2 (0.42) | KDM5BKDM5AKDM6BKDM4AKDM4D | |
| SCHEMBL25352337 | 0.76 | PRKAB2 (0.35) | KDM5BKDM5AALDH1A1KDM4C | |
| SCHEMBL22637695 | 0.76 | HCAR2 (0.49) | KDM5BKDM5ASMN1; SMN2TDP1KDM4C | |
| SCHEMBL20267445 | 0.75 | GABRP (0.50) | KDM5BKDM6BKDM4AKDM4DKDM3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113423709-B | Triazinone imidazole compound and medical application thereof | 四川科伦博泰生物医药股份有限公司 | 2024-02-09 | — | — | CN | disclosed |
| WO-2023154519-A1 | INHIBITORS OF RNA HELICASE DHX9 AND USES THEREOF | ACCENT THERAPEUTICS, INC. (US) | 2023-08-17 | — | — | WO | disclosed |
| WO-2020207352-A1 | TRIAZINE BENZIMIDAZOLE COMPOUNDS AND MEDICAL USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2020-10-15 | — | — | WO | disclosed |