Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 9/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CDC25B | P30305 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.37 |
| ▸ | GGT1 | P19440 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2831679 | 0.76 | CHEK1 (0.31) | ALDH1A1ALOX15TDP1HSD17B10PTGS1 | |
| SCHEMBL10382826 | 0.74 | MEN1 (0.35) | ALDH1A1ALOX15HTTTDP1TSHR | |
| SCHEMBL7130790 | 0.74 | LMNA (0.43) | LMNAALDH1A1PTPN1KDM4ETSHR | |
| SCHEMBL5524626 | 0.73 | ALDH1A1 (0.48) | LMNAALDH1A1ALOX15HTTPTPN1 | |
| SCHEMBL8816297 | 0.71 | ALDH1A1 (0.40) | ALDH1A1MAPTTDP1POLBTSHR | |
| SCHEMBL7429745 | 0.70 | NFE2L2 (0.36) | — | |
| SCHEMBL1690946 | 0.69 | ALDH1A1 (0.39) | LMNAALDH1A1ALOX15HTTPTPN1 | |
| SCHEMBL9280537 | 0.68 | ALDH1A1 (0.46) | LMNAALDH1A1ALOX15PTPN1KDM4E | |
| SCHEMBL18158039 | 0.68 | ALDH1A1 (0.56) | LMNAALDH1A1ALOX15HTTPTPN1 | |
| SCHEMBL972143 | 0.68 | ALDH1A1 (0.56) | LMNAALDH1A1ALOX15HTTPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6828392-B2 | For use as solid supports for organic synthesis, for enzymatic assays, for immobilization of biomolecules, for controlled release of drugs, and for chromatographic separations | CARLSBERG A/S (DK) | 2004-12-07 | — | — | US | disclosed |
| US-20030096918-A1 | Hydroxy and amine functionalised resins | CARLSBERG A/S (DK) | 2003-05-22 | — | — | US | disclosed |