Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 2/20 | 0.49 |
| ▸ | KMO | O15229 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | AR | P10275 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29746381 | 0.98 | CTSS (0.54) | CTSSCNR2KDM4EHPGDATM | |
| SCHEMBL1416671 | 0.98 | CTSS (0.54) | CTSSCNR2KDM4EHPGDATM | |
| SCHEMBL26819706 | 0.91 | NPC1 (0.51) | CTSSCNR2KDM4EHPGDATM | |
| SCHEMBL6859602 | 0.82 | NPC1 (0.61) | KDM4EHPGDNPC1RAB9ACYP3A4 | |
| SCHEMBL17449881 | 0.81 | RAB9A (0.62) | KDM4EHPGDNPC1RAB9ACYP3A4 | |
| SCHEMBL13854087 | 0.80 | CTSS (0.58) | CTSSCNR2KDM4EHPGDKDM1A | |
| SCHEMBL29544777 | 0.80 | NPC1 (0.62) | KDM4EHPGDNPC1RAB9ACYP3A4 | |
| SCHEMBL22734790 | 0.80 | NPC1 (0.62) | KDM4EHPGDNPC1RAB9ACYP3A4 | |
| SCHEMBL27930179 | 0.80 | NPC1 (0.50) | CNR2KDM4EHPGDATMNPC1 | |
| SCHEMBL14730878 | 0.78 | NPC1 (0.60) | CTSSKMOIDO1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6835469-B2 | Phosphorescent compounds and devices comprising the same | THE UNIVERSITY OF SOUTHERN CALIFORNIA | 2004-12-28 | — | — | US | disclosed |