Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1027914 | 0.82 | CYP2D6 (0.40) | ALDH1A1ALOX15TSHRHSD17B10CYP2D6 | |
| SCHEMBL1028410 | 0.78 | ALDH1A1 (0.45) | ALDH1A1CYP3A4ALOX15TSHRALOX12 | |
| SCHEMBL27761972 | 0.71 | ALDH1A1 (0.47) | ALDH1A1CYP3A4ALOX15TSHRALOX12 | |
| SCHEMBL1030258 | 0.70 | SCN10A (0.34) | ALDH1A1MAPK1NPC1PLA2G1BNFKB1 | |
| SCHEMBL6682450 | 0.69 | CYP2D6 (0.33) | ALDH1A1CYP2D6NPC1PLA2G1BNFKB1 | |
| SCHEMBL6682446 | 0.69 | KCNH3 (0.34) | ALDH1A1CYP3A4ALOX15TSHRALOX12 | |
| SCHEMBL1032197 | 0.66 | ALDH1A1 (0.35) | ALDH1A1CYP3A4ALOX15TSHRALOX12 | |
| SCHEMBL1030639 | 0.66 | HSP90AA1 (0.39) | ALDH1A1ALOX15HIF1AHSD17B10CYP2D6 | |
| SCHEMBL1032660 | 0.64 | CYP1A2 (0.37) | ALDH1A1ALOX15TSHRMAPK1HIF1A | |
| SCHEMBL1031002 | 0.63 | ALDH1A1 (0.43) | ALDH1A1CYP3A4ALOX15TSHRCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1474377-A1 | NITROSOPHENOLS AND C-NITROSOANILINES AS POLYMERIZATION INHIBITORS | Crompton Corporation (US) | 2004-11-10 | — | — | EP | disclosed |
| WO-2003070687-A1 | NITROSOPHENOLS AND C-NITROSOANILINES AS POLYMERIZATION INHIBITORS | CROMPTON CORPORATION (US) | 2003-08-28 | — | — | WO | disclosed |