Tetrahydrocannabivarin

Tetrahydrocannabivarin

SCHEMBL6856739

CCCc1cc(O)c2c(c1)OC(C)(C)[C@@H]1CCC(C)=C[C@@H]21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 16/20 1.00
CNR1 P21554 14/20 1.00
TRPM8 Q7Z2W7 2/20 1.00
GPR55 Q9Y2T6 2/20 1.00
TRPA1 O75762 1/20 1.00
HTR1A P08908 1/20 1.00
TRPV1 Q8NER1 1/20 1.00
TRPV3 Q8NET8 1/20 1.00
TRPV6 Q9H1D0 1/20 1.00
TRPV4 Q9HBA0 1/20 1.00
TRPV5 Q9NQA5 1/20 1.00
TRPV2 Q9Y5S1 1/20 1.00
ABHD12 Q8N2K0 3/20 0.86
ABHD6 Q9BV23 3/20 0.86
FAAH O00519 2/20 0.86
NR1I2 O75469 1/20 0.86
LDHA P00338 1/20 0.86
GLRA1 P23415 1/20 0.86
GPR183 P32249 1/20 0.86
DRD3 P35462 1/20 0.86

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetrahydrocannabivarin SCHEMBL29904669 1.00 CNR2 (1.00) CNR2CNR1TRPM8GPR55TRPA1
Tetrahydrocannabivarin SCHEMBL29422123 1.00 CNR2 (1.00) CNR2CNR1TRPM8GPR55TRPA1
Tetrahydrocannabivarin SCHEMBL30017852 1.00 CNR2 (1.00) CNR2CNR1TRPM8GPR55TRPA1
Tetrahydrocannabivarin SCHEMBL31300003 1.00 CNR2 (1.00) CNR2CNR1TRPM8GPR55TRPA1
Tetrahydrocannabivarin SCHEMBL31544930 1.00 CNR2 (1.00) CNR2CNR1TRPM8GPR55TRPA1
Tetrahydrocannabivarin SCHEMBL18371743 1.00 CNR2 (1.00) CNR2CNR1TRPM8GPR55TRPA1
Tetrahydrocannabivarin SCHEMBL29350511 1.00 CNR2 (1.00) CNR2CNR1TRPM8GPR55TRPA1
Tetrahydrocannabivarin SCHEMBL245827 1.00 CNR2 (1.00) CNR2CNR1TRPM8GPR55TRPA1
Tetrahydrocannabivarin SCHEMBL21363566 1.00 CNR2 (1.00) CNR2CNR1TRPM8GPR55TRPA1
Tetrahydrocannabivarin SCHEMBL25731794 1.00 CNR2 (1.00) CNR2CNR1TRPM8GPR55TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 423 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240315965-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2024-09-26 US claimed
US-20230190670-A1 COMPOSITIONS COMPRISING NOVEL CANNABINOID AND TERPENE PROFILES Natural Extraction Systems, LLC (US) 2023-06-22 US claimed
US-20230089351-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2023-03-23 US claimed
WO-2022182527-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2022-09-01 WO claimed
WO-2021158573-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2021-08-12 WO claimed
WO-2021158575-A1 COMPOSITIONS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2021-08-12 WO claimed
WO-2021127559-A1 COMPOSITIONS COMPRISING CANNABINOID ANIONS AND ANTI-NUCLEATING AGENTS Natural Extraction Systems, LLC (US) 2021-06-24 WO claimed
WO-2021113261-A1 COMPOSITIONS COMPRISING NOVEL CANNABINOID AND TERPENE PROFILES Natural Extraction Systems, LLC (US) 2021-06-10 WO claimed
US-10807931-B2 Synthesis of phytocannabinoids including a decarboxylation step THE UNIVERSITY OF SYDNEY (AU) 2020-10-20 US claimed
US-20200172459-A1 SYNTHESIS OF PHYTOCANNABINOIDS INCLUDING A DECARBOXYLATION STEP THE UNIVERSITY OF SYDNEY (AU) 2020-06-04 US claimed
EP-3962296-B1 CANNABINOID COMPOSITIONS AND METHODS OF USING GREENWAY HERBAL PRODUCTS LLC (US) 2026-04-29 EP disclosed
US-12582663-B2 Compositions comprising decarboxylated cannabinoids Natural Extraction Systems, LLC (US) 2026-03-24 US disclosed
US-20260077009-A1 COMPOSITIONS AND METHODS FOR TREATING NEUROLOGICAL DISORDERS Neurotech International Ltd (AU) 2026-03-19 US disclosed
US-20250380732-A1 AEROSOLISABLE FORMULATION NICOVENTURES TRADING LTD (GB) 2025-12-18 US disclosed
US-20250368594-A1 COMPOSITIONS AND METHODS TO SEPARATE CANNABINOIDS FROM IMPURITIES BY CRYSTALLIZATION NATURAL EXTRACTION SYS LLC (US) 2025-12-04 US disclosed
US-20130059018-A1 PHYTOCANNABINOIDS IN THE TREATMENT OF CANCER OTSUKA PHARMACEUTICAL CO., LIMITED (JP) 2013-03-07 US disclosed
US-20130059018-A1 PHYTOCANNABINOIDS IN THE TREATMENT OF CANCER OTSUKA PHARMACEUTICAL CO., LIMITED (JP) 2013-03-07 US disclosed
WO-2011110866-A1 PHYTOCANNABINOIDS IN THE TREATMENT OF CANCER GW PHARMA LIMITED (GB) 2011-09-15 WO disclosed
US-20100204312-A1 METHODS AND COMPOSITIONS FOR TREATING CANCER CALIFORNIA PACIFIC MEDICAL CENTER (US) 2010-08-12 US disclosed
US-20100204312-A1 METHODS AND COMPOSITIONS FOR TREATING CANCER CALIFORNIA PACIFIC MEDICAL CENTER (US) 2010-08-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230089351-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES FABP2, FABP4, GUSB CNR2 3068/4885CNR1 3464/4885TRPM8 1161/4885
US-20200172459-A1 SYNTHESIS OF PHYTOCANNABINOIDS INCLUDING A DECARBOXYLATION STEP CNR2, CNR1, CCNB1 CNR2 1/4885CNR1 2/4885TRPM8 2093/4885
US-20130059018-A1 PHYTOCANNABINOIDS IN THE TREATMENT OF CANCER CNR1, CNR2, LSS CNR2 2/4885CNR1 1/4885TRPM8 2241/4885
US-20260077009-A1 COMPOSITIONS AND METHODS FOR TREATING NEUROLOGICAL DISORDERS CNR2, CNR1, SNCA CNR2 1/4885CNR1 2/4885TRPM8 351/4885
US-20100204312-A1 METHODS AND COMPOSITIONS FOR TREATING CANCER CNR2, CNR1, JUP CNR2 1/4885CNR1 2/4885TRPM8 2766/4885
US-12582663-B2 Compositions comprising decarboxylated cannabinoids GGPS1, PGGT1B, CNR2 CNR2 3/4885CNR1 8/4885TRPM8 2217/4885
US-10807931-B2 Synthesis of phytocannabinoids including a decarboxylation step CNR2, CNR1, CCNB1 CNR2 1/4885CNR1 2/4885TRPM8 2093/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.