Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 1/20 | 0.79 |
| ▸ | KDM6B | O15054 | 1/20 | 0.69 |
| ▸ | KDM6A | O15550 | 1/20 | 0.69 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | HPGD | P15428 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | USP2 | O75604 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | ESR1 | P03372 | 5/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.53 |
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL56592 | 0.98 | TOP2A (0.82) | TOP2AKDM6BKDM6APTGS2ALDH1A1 | |
| SCHEMBL29401377 | 0.98 | TOP2A (0.82) | TOP2AKDM6BKDM6APTGS2ALDH1A1 | |
| SCHEMBL1888141 | 0.96 | TOP2A (0.79) | TOP2AKDM6BKDM6APTGS2ALDH1A1 | |
| Lithium SCHEMBL6864068 | 0.96 | TOP2A (0.79) | TOP2AKDM6BKDM6APTGS2ALDH1A1 | |
| SCHEMBL17385621 | 0.96 | TOP2A (0.79) | TOP2AKDM6BKDM6APTGS2ALDH1A1 | |
| SCHEMBL1549736 | 0.96 | TOP2A (0.79) | TOP2AKDM6BKDM6APTGS2ALDH1A1 | |
| SCHEMBL1377496 | 0.96 | TOP2A (0.79) | TOP2AKDM6BKDM6APTGS2ALDH1A1 | |
| SCHEMBL1550650 | 0.96 | TOP2A (0.79) | TOP2AKDM6BKDM6APTGS2ALDH1A1 | |
| SCHEMBL1550613 | 0.96 | TOP2A (0.79) | TOP2AKDM6BKDM6APTGS2ALDH1A1 | |
| SCHEMBL1549620 | 0.96 | TOP2A (0.79) | TOP2AKDM6BKDM6APTGS2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6800380-B2 | BENZOXAZOLE- OR BENZTHIAZOLE-METAL COMPLEXES; HIGH THERMAL STABILITY: EMIT PURE BLUE LIGHT | NESSDISPLAY CO., LTD. (KR) | 2004-10-05 | — | — | US | disclosed |
| US-20030165711-A1 | Novel organometallic luminescent materials and organic electroluminescent device containing same | DONGJIN SEMICHEM CO., LTD. (KR) | 2003-09-04 | — | — | US | disclosed |
| US-6579633-B2 | Metal sulfonates of metal complexes of hydroxy- and mercapto-quinolines, benzoxazoles, benzothiazoles, benzotriazoles, benzoselenazoles, benzotellurazoles and phenanthridines | NESSDISPLAY CO., LTD. (KR) | 2003-06-17 | — | — | US | disclosed |
| US-6534201-B2 | Metal sulfonates of metal complexes of hydroxy- and mercapto-quinolines, benzoxazoles, benzothiazoles, benzotriazoles, benzoselenazoles, benzotellurazoles and phenanthridines | DONGJIN SEMICHEM CO., LTD. (KR) | 2003-03-18 | — | — | US | disclosed |
| US-20020045063-A1 | Novel organometallic luminescent materials and organic electroluminescent device containing same | NESSDISPLAY CO., LTD. | 2002-04-18 | — | — | US | disclosed |
| US-20020045064-A1 | Novel organometallic luminescent materials and organic electroluminescent device containing same | NESSDISPLAY CO., LTD. | 2002-04-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030165711-A1 | Novel organometallic luminescent materials and organic electroluminescent device containing same | SOD1, MB, IK | TOP2A 4443/4885KDM6B 2831/4885KDM6A 2874/4885 |
| US-20020045063-A1 | Novel organometallic luminescent materials and organic electroluminescent device containing same | IK, LAGE3, NDUFV2 | TOP2A 3287/4885KDM6B 2192/4885KDM6A 2094/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.