Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 2/20 | 0.39 |
| ▸ | AVPR1B | P47901 | 3/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | MRE11 | P49959 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.33 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.33 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6856961 | 0.85 | SMN1; SMN2 (0.39) | PTGESAVPR1BMAOB | |
| SCHEMBL6857475 | 0.78 | AVPR1B (0.54) | AVPR1B | |
| SCHEMBL6857173 | 0.78 | AVPR1B (0.45) | AVPR1B | |
| SCHEMBL6856859 | 0.78 | AVPR1B (0.47) | AVPR1BMAOB | |
| SCHEMBL6857409 | 0.77 | AVPR1B (0.43) | AVPR1BMAOBKMT2A | |
| SCHEMBL6857161 | 0.73 | AVPR1B (0.43) | AVPR1B | |
| SCHEMBL16423646 | 0.72 | AVPR1B (0.45) | AVPR1BKDM4EALDH1A1 | |
| SCHEMBL6857370 | 0.72 | TRPV1 (0.39) | AVPR1BKDM4ECNR1 | |
| SCHEMBL1687280 | 0.71 | AVPR1B (0.41) | AVPR1BKDM4EALDH1A1 | |
| SCHEMBL6857026 | 0.67 | AVPR1B (0.48) | AVPR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011096461-A1 | QUINOLINE DERIVATIVE | 大正製薬株式会社 (JP) | 2011-08-11 | — | — | WO | disclosed |