Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1B | P47901 | 8/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | AXL | P30530 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6854936 | 0.90 | AVPR1B (0.41) | AVPR1BENPP2MCHR1ACACB | |
| SCHEMBL6856269 | 0.86 | AVPR1B (0.40) | AVPR1BAXLEGFRF10KDM4E | |
| SCHEMBL6857500 | 0.86 | AVPR1B (0.41) | AVPR1BAXLMAPTENPP2MCHR1 | |
| SCHEMBL6856813 | 0.85 | AVPR1B (0.40) | AVPR1BKDM4EALDH1A1MAPTENPP2 | |
| SCHEMBL6855979 | 0.81 | AVPR1B (0.39) | AVPR1BKDM4E | |
| SCHEMBL6857461 | 0.81 | AVPR1B (0.44) | AVPR1BACACB | |
| SCHEMBL6856235 | 0.80 | AVPR1B (0.39) | AVPR1BKDM4EMAPT | |
| SCHEMBL16445234 | 0.79 | AVPR1B (0.49) | AVPR1BSOS1 | |
| SCHEMBL6856705 | 0.78 | AVPR1B (0.58) | AVPR1BAXL | |
| SCHEMBL6857414 | 0.78 | AVPR1B (0.38) | AVPR1BACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011096461-A1 | QUINOLINE DERIVATIVE | 大正製薬株式会社 (JP) | 2011-08-11 | — | — | WO | disclosed |