Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1B | P47901 | 11/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6854936 | 0.87 | AVPR1B (0.41) | AVPR1BACACBCASP3ENPP2 | |
| SCHEMBL6856891 | 0.85 | AVPR1B (0.40) | AVPR1BACACBENPP2KDM4EALDH1A1 | |
| SCHEMBL6857500 | 0.84 | AVPR1B (0.41) | AVPR1BACACBENPP2MAPT | |
| SCHEMBL6857461 | 0.80 | AVPR1B (0.44) | AVPR1BACACB | |
| SCHEMBL6855979 | 0.79 | AVPR1B (0.39) | AVPR1BKDM4E | |
| SCHEMBL6856235 | 0.79 | AVPR1B (0.39) | AVPR1BKDM4ETDP1MAPT | |
| SCHEMBL6856705 | 0.76 | AVPR1B (0.58) | AVPR1B | |
| SCHEMBL6856801 | 0.76 | HRH3 (0.43) | AVPR1BACACB | |
| SCHEMBL6855740 | 0.76 | AVPR1B (0.51) | AVPR1B | |
| SCHEMBL6857432 | 0.75 | AVPR1B (0.43) | AVPR1BMEN1KMT2AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011096461-A1 | QUINOLINE DERIVATIVE | 大正製薬株式会社 (JP) | 2011-08-11 | — | — | WO | disclosed |