Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1B | P47901 | 13/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6857026 | 0.88 | AVPR1B (0.48) | AVPR1B | |
| SCHEMBL6856938 | 0.86 | PTGDR2 (0.44) | NAMPT | |
| SCHEMBL6857383 | 0.84 | AVPR1B (0.42) | AVPR1B | |
| SCHEMBL6856805 | 0.83 | AVPR1B (0.45) | AVPR1BTP53SMN1; SMN2NPC1RAB9A | |
| SCHEMBL6857380 | 0.80 | TRPV1 (0.38) | AVPR1B | |
| SCHEMBL6856187 | 0.80 | AVPR1B (0.65) | AVPR1B | |
| SCHEMBL6856859 | 0.76 | AVPR1B (0.47) | AVPR1B | |
| SCHEMBL6856660 | 0.76 | AVPR1B (0.51) | AVPR1B | |
| SCHEMBL6857216 | 0.74 | AVPR1B (0.49) | AVPR1BSMN1; SMN2 | |
| SCHEMBL6857409 | 0.73 | AVPR1B (0.43) | AVPR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011096461-A1 | QUINOLINE DERIVATIVE | 大正製薬株式会社 (JP) | 2011-08-11 | — | — | WO | disclosed |