Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.44 |
| ▸ | VDR | P11473 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.42 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | GRK6 | P43250 | 1/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6857161 | 0.86 | AVPR1B (0.43) | NAMPT | |
| SCHEMBL6856940 | 0.84 | RXRA (0.41) | PTGDR2RXRARXRBCSNK2A2CSNK2B | |
| SCHEMBL6856287 | 0.82 | CSNK2A2 (0.43) | VDRPPARDRXRARXRBCSNK2A2 | |
| SCHEMBL4052652 | 0.76 | PTGDR2 (0.47) | PTGDR2VDRPPARDRXRARXRB | |
| SCHEMBL4166291 | 0.73 | KCNA5 (0.59) | PTGDR2VDRPPARDRXRARXRB | |
| SCHEMBL6856805 | 0.73 | AVPR1B (0.45) | CSNK2A2CSNK2BALDH1A1KDM4E | |
| SCHEMBL3384876 | 0.73 | KDM4E (0.53) | PTGDR2ALDH1A1HSD17B10MAPTKDM4E | |
| SCHEMBL24744927 | 0.71 | KDM4E (0.58) | ALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL6857383 | 0.70 | AVPR1B (0.42) | — | |
| SCHEMBL10509302 | 0.70 | KDM4E (0.65) | PTGDR2ALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011096461-A1 | QUINOLINE DERIVATIVE | 大正製薬株式会社 (JP) | 2011-08-11 | — | — | WO | disclosed |