SCHEMBL68574

SCHEMBL68574

COc1ccc2c(c1)SCC2=O

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.71
HTT P42858 1/20 0.71
ALDH1A1 P00352 1/20 0.58
MAOA P21397 1/20 0.57
MAOB P27338 1/20 0.57
LMNA P02545 1/20 0.54
CA9 Q16790 7/20 0.47
CA1 P00915 6/20 0.47
CA2 P00918 6/20 0.47
CA12 O43570 6/20 0.47
RYR2 Q92736 1/20 0.45
EGFR P00533 1/20 0.45
KDR P35968 1/20 0.44
METAP1 P53582 1/20 0.44
CA4 P22748 2/20 0.43
CA7 P43166 2/20 0.43
CA3 P07451 1/20 0.43
CA6 P23280 1/20 0.43
CA5A P35218 1/20 0.43
CA13 Q8N1Q1 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8118067 0.86 RYR2 (0.56) KDM4EHTTALDH1A1MAOAMAOB
SCHEMBL67590 0.83 KDM4E (1.00) KDM4EHTTALDH1A1MAOAMAOB
SCHEMBL6366190 0.80 KDM4E (0.82) KDM4EHTTALDH1A1MAOAMAOB
SCHEMBL29853726 0.79 CA12 (0.53) KDM4EHTTALDH1A1MAOAMAOB
SCHEMBL26768607 0.79 CA12 (0.53) KDM4EHTTALDH1A1MAOAMAOB
SCHEMBL13871409 0.76 EPHX2 (0.53) KDM4EHTTALDH1A1MAOAMAOB
SCHEMBL22451348 0.75 KDM4E (0.56) KDM4EHTTALDH1A1MAOAMAOB
SCHEMBL31260280 0.75 ALDH1A1 (0.57) KDM4EHTTALDH1A1MAOAMAOB
SCHEMBL1987343 0.75 ALDH1A1 (0.57) KDM4EHTTALDH1A1MAOAMAOB
SCHEMBL31260278 0.75 ALDH1A1 (0.57) KDM4EHTTALDH1A1MAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9211725-B2 Inkjet recording method and printed material FUJIFILM CORPORATION (JP) 2015-12-15 US disclosed
EP-2682272-B1 INK JET RECORDING METHOD AND PRINTED MATERIAL FUJIFILM CORP (JP) 2015-08-26 EP disclosed
US-8378002-B2 Aqueous ink composition, aqueous ink composition for inkjet recording, and inkjet recording method FUJIFILM CORPORATION (JP) 2013-02-19 US disclosed
US-8378002-B2 Aqueous ink composition, aqueous ink composition for inkjet recording, and inkjet recording method FUJIFILM CORPORATION (JP) 2013-02-19 US disclosed
EP-1831207-B1 AMINOPYRIMIDINE COMPOUNDS AS PLK INHIBITORS AMGEN INC (US) 2012-11-14 EP disclosed
US-8168263-B2 Photo-curable composition, ink composition, and inkjet recording method using the ink composition FUJIFILM CORPORATION (JP) 2012-05-01 US disclosed
US-8168263-B2 Photo-curable composition, ink composition, and inkjet recording method using the ink composition FUJIFILM CORPORATION (JP) 2012-05-01 US disclosed
US-8147921-B2 Ink set for inkjet recording and inkjet recording method FUJIFILM CORPORATION (JP) 2012-04-03 US disclosed
US-8147921-B2 Ink set for inkjet recording and inkjet recording method FUJIFILM CORPORATION (JP) 2012-04-03 US disclosed
US-8128843-B2 Photocurable composition, photocurable ink composition, process for producing photocured material, and inkjet recording method FUJIFILM CORPORATION (JP) 2012-03-06 US disclosed
US-20080182031-A1 Sensitizing dye, an alpha-aminoketone or acyl phosphine oxide polymerization initiator and an ethylenically unsaturated bond-containing polymerizable compound FUJIFILM CORPORATION (JP) 2008-07-31 US disclosed
EP-1944173-A1 Ink composition and inkjet recording method using the same FUJIFILM Corporation (JP) 2008-07-16 EP disclosed
EP-1831207-A1 AMINOPYRIMIDINE COMPOUNDS AND METHODS OF USE Amgen Inc. (US) 2007-09-12 EP disclosed
US-20070185133-A1 Aminopyrimidine compounds and methods of use AMGEN, INC. (US) 2007-08-09 US disclosed
WO-2006066172-A1 AMINOPYRIMIDINE COMPOUNDS AND METHODS OF USE AMGEN, INC. (US) 2006-06-22 WO disclosed
US-20020086895-A1 Methods of treating fungal infections CHU WAI-LAM ALEX (US) 2002-07-04 US disclosed
EP-1005338-A4 SUBSTITUTED AURONE DERIVATIVES PHYTERA INC (US) 2001-11-07 EP disclosed
US-6307070-B1 FUNGICIDES PHYTERA, INC. 2001-10-23 US disclosed
EP-1005338-A1 SUBSTITUTED AURONE DERIVATIVES PHYTERA, INC. (US) 2000-06-07 EP disclosed
WO-1999004789-A1 SUBSTITUTED AURONE DERIVATIVES PHYTERA, INC. (US) 1999-02-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020086895-A1 Methods of treating fungal infections COXFA4L2, DPM1, ERG28 KDM4E 2808/4885HTT 4866/4885ALDH1A1 1149/4885
US-20070185133-A1 Aminopyrimidine compounds and methods of use PLK1, TYMP, TK2 KDM4E 1956/4885HTT 2363/4885ALDH1A1 1565/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.