Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7717242 | 0.90 | AKR1C4 (0.39) | NLRP3AKR1C4AKR1C3AKR1C2THRB | |
| SCHEMBL8022057 | 0.90 | AKR1C4 (0.39) | NLRP3AKR1C4AKR1C3AKR1C2THRB | |
| SCHEMBL7717295 | 0.90 | AKR1C4 (0.39) | NLRP3AKR1C4AKR1C3AKR1C2THRB | |
| SCHEMBL7719151 | 0.90 | AKR1C4 (0.39) | NLRP3AKR1C4AKR1C3AKR1C2THRB | |
| SCHEMBL6865569 | 0.79 | NLRP3 (0.39) | NLRP3THRBLMNASMN1; SMN2 | |
| SCHEMBL6865571 | 0.79 | NLRP3 (0.39) | NLRP3THRBLMNASMN1; SMN2 | |
| SCHEMBL6865568 | 0.79 | NLRP3 (0.39) | NLRP3THRBLMNASMN1; SMN2 | |
| SCHEMBL7717289 | 0.78 | — | — | |
| SCHEMBL7717286 | 0.78 | — | — | |
| SCHEMBL8205330 | 0.77 | NPC1 (0.42) | NLRP3CYP2D6NPC1LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0999204-B1 | NOVEL COMPOUND HAVING EFFECT OF PROMOTING NEURON DIFFERENTIATION | NIPPON KAYAKU KK (JP) | 2004-10-13 | — | — | EP | disclosed |
| US-6384063-B1 | Compound having effect of promoting neuron differentiation | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2002-05-07 | — | — | US | disclosed |
| EP-0999204-A1 | NOVEL COMPOUND HAVING EFFECT OF PROMOTING NEURON DIFFERENTIATION | Nippon Kayaku Kabushiki Kaisha (JP) | 2000-05-10 | — | — | EP | disclosed |