Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Nitric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nitric Acid SCHEMBL1400913 | 0.81 | ALDH1A1 (0.43) | ALDH1A1TDP1 | |
| Nitric Acid SCHEMBL441121 | 0.81 | CA5A (0.42) | ALDH1A1 | |
| Nitric Acid SCHEMBL442182 | 0.81 | ALDH1A1 (0.43) | ALDH1A1TDP1 | |
| Nitric Acid SCHEMBL6858001 | 0.74 | CA5A (0.32) | LMNA | |
| SCHEMBL29165147 | 0.70 | THRB (0.56) | ALDH1A1LMNA | |
| Nitric Acid SCHEMBL11148137 | 0.69 | ALDH1A1 (0.40) | ALDH1A1LMNATDP1 | |
| Nitric Acid SCHEMBL31295856 | 0.69 | ALDH1A1 (0.42) | ALDH1A1 | |
| Nitric Acid SCHEMBL10950758 | 0.69 | ALDH1A1 (0.40) | ALDH1A1LMNATDP1 | |
| Propanol SCHEMBL5573890 | 0.67 | — | — | |
| Nitric Acid SCHEMBL8290821 | 0.67 | CA5A (0.53) | ALDH1A1LMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11802099-B2 | Or relating to energetic materials | LEWTAS SCIENCE & TECHNOLOGIES LTD (GB) | 2023-10-31 | — | — | US | disclosed |
| US-20200148609-A1 | IMPROVEMENTS IN OR RELATING TO ENERGETIC MATERIALS | LEWTAS SCIENCE & TECHNOLOGIES LTD (GB) | 2020-05-14 | — | — | US | disclosed |
| EP-3609858-A1 | IMPROVEMENTS IN OR RELATING TO ENERGETIC MATERIALS | Lewtas Science & Technologies Ltd (GB) | 2020-02-19 | — | — | EP | disclosed |
| US-20180305270-A1 | IMPROVEMENTS IN OR RELATING TO ENERGETIC MATERIALS | LEWTAS SCIENCE & TECHNOLOGIES LTD (GB) | 2018-10-25 | — | — | US | disclosed |
| WO-2018189158-A1 | IMPROVEMENTS IN OR RELATING TO ENERGETIC MATERIALS | LEWTAS SCIENCE & TECHNOLOGIES LTD (GB) | 2018-10-18 | — | — | WO | disclosed |
| EP-3362422-A1 | IMPROVEMENTS IN OR RELATING TO ENERGETIC MATERIALS | Lewtas Science & Technologies Ltd (GB) | 2018-08-22 | — | — | EP | disclosed |
| WO-2017064102-A1 | IMPROVEMENTS IN OR RELATING TO ENERGETIC MATERIALS | LEWTAS SCIENCE & TECHNOLOGIES LTD (GB) | 2017-04-20 | — | — | WO | disclosed |
| US-8864923-B1 | Ballistic modifier formulation for double base propellant | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2014-10-21 | — | — | US | disclosed |
| US-8828161-B1 | Ballistic modification and solventless double base propellant, and process thereof | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 2014-09-09 | — | — | US | disclosed |
| US-6833037-B1 | Thermoplastic resin, high energy filler, and polymeric binder blend comprising ethylene-vinyl acetate copolymer and acrylonitrile-butadiene copolymer; gun and rocket propellants | BAE SYSTEMS PLC (GB) | 2004-12-21 | — | — | US | disclosed |