Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.58 |
| ▸ | CASP7 | P55210 | 3/20 | 0.50 |
| ▸ | CASP3 | P42574 | 3/20 | 0.50 |
| ▸ | CASP6 | P55212 | 2/20 | 0.50 |
| ▸ | CASP8 | Q14790 | 2/20 | 0.50 |
| ▸ | CASP2 | P42575 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | RGS12 | O14924 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16754925 | 0.81 | GSK3B (0.62) | GSK3BCASP7CASP3CASP6CASP8 | |
| Phthalimide SCHEMBL9561193 | 0.78 | GSK3B (0.94) | GSK3BCASP7CASP3CASP6CASP8 | |
| SCHEMBL7806626 | 0.78 | GSK3B (0.52) | GSK3BCASP7CASP3CASP6CASP8 | |
| SCHEMBL5616554 | 0.78 | GSK3B (0.52) | GSK3BCASP7CASP3CASP6CASP8 | |
| Phthalimide SCHEMBL29664386 | 0.76 | GSK3B (0.88) | GSK3BCASP7CASP3CASP6CASP8 | |
| Phthalimide SCHEMBL11040503 | 0.75 | GSK3B (1.00) | GSK3BCASP7CASP3CASP6CASP8 | |
| Phthalimide SCHEMBL29366030 | 0.75 | GSK3B (1.00) | GSK3BCASP7CASP3CASP6CASP8 | |
| Phthalimide SCHEMBL30125197 | 0.75 | GSK3B (1.00) | GSK3BCASP7CASP3CASP6CASP8 | |
| Phthalimide SCHEMBL64 | 0.75 | GSK3B (1.00) | GSK3BCASP7CASP3CASP6CASP8 | |
| Phthalimide SCHEMBL7771670 | 0.75 | GSK3B (1.00) | GSK3BCASP7CASP3CASP6CASP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0331375-B1 | Optical elements for radiation comprising graphite films | MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) | 1995-08-23 | — | — | EP | claimed |
| JP-2173045-A | — | — | None | — | — | JP | disclosed |
| EP-1446850-A1 | COOLING DEVICE FOR ELECTRICAL SYSTEMS AND USE OF POLYMERS IN COOLING CIRCUITS | Ticona GmbH (DE) | 2004-08-18 | — | — | EP | disclosed |
| WO-2003041198-A1 | COOLING DEVICE FOR ELECTRICAL SYSTEMS AND USE OF POLYMERS IN COOLING CIRCUITS | TICONA GMBH (DE) | 2003-05-15 | — | — | WO | disclosed |
| JP-H02173045-A | SURFACE TREATMENT OF AROMATIC POLYAMIDE | MITSUI TOATSU CHEM INC | 1990-07-04 | — | — | JP | disclosed |