Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.52 |
| ▸ | CASP3 | P42574 | 3/20 | 0.45 |
| ▸ | CASP2 | P42575 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | CASP6 | P55212 | 1/20 | 0.45 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.45 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.45 |
| ▸ | WEE1 | P30291 | 2/20 | 0.45 |
| ▸ | PARP1 | P09874 | 2/20 | 0.44 |
| ▸ | PTP4A3 | O75365 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | ADK | P55263 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL135332 | 0.92 | GSK3B (0.56) | GSK3BCASP3CASP2CASP7CASP6 | |
| SCHEMBL29032840 | 0.90 | GSK3B (0.54) | GSK3BCASP3CASP2CASP7CASP6 | |
| Ammonia Solution, Strong SCHEMBL28821133 | 0.90 | GSK3B (0.54) | GSK3BCASP3CASP2CASP7CASP6 | |
| SCHEMBL16754925 | 0.85 | GSK3B (0.62) | GSK3BCASP3CASP2CASP7CASP6 | |
| SCHEMBL8429414 | 0.84 | GSK3B (0.61) | GSK3BCASP3CASP2CASP7CASP6 | |
| SCHEMBL9016868 | 0.80 | GSK3B (0.50) | GSK3BCASP3CASP2CASP7CASP6 | |
| SCHEMBL28938878 | 0.80 | PTPRC (0.46) | GSK3BCASP3CASP2CASP7CASP6 | |
| Biphenyl SCHEMBL27584116 | 0.78 | GSK3B (0.48) | GSK3BCASP3CASP2CASP7CASP6 | |
| SCHEMBL6858237 | 0.78 | GSK3B (0.58) | GSK3BCASP3CASP2CASP7CASP6 | |
| SCHEMBL28839558 | 0.78 | GSK3B (0.44) | GSK3BCASP3CASP2CASP7CASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070219344-A1 | HIGH HEAT POLYETHERSULFONE COMPOSITIONS | GENERAL ELECTRIC COMPANY (US) | 2007-09-20 | — | — | US | disclosed |