Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | TNK1 | Q13470 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.31 |
| ▸ | TUBB | P07437 | 1/20 | 0.31 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.31 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.31 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.31 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.31 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.31 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.31 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.31 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.31 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.31 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.31 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6854844 | 0.80 | MAT2A (0.43) | ALDH1A1TSHRMAPK1PARP1LMNA | |
| SCHEMBL6855823 | 0.78 | PIM1 (0.35) | ALDH1A1MAPTMEN1KMT2ARAB9A | |
| SCHEMBL6858242 | 0.77 | HPGD (0.41) | ALDH1A1TSHRPARP1KDM4EMAPT | |
| SCHEMBL6858383 | 0.62 | MAPT (0.45) | LMNAMAPTMEN1KMT2A | |
| SCHEMBL6853905 | 0.60 | L3MBTL1 (0.47) | ALDH1A1MAPK1LMNAKDM4EMAPT | |
| SCHEMBL15850291 | 0.60 | CHKA (0.47) | ALDH1A1TSHRMAPK1LMNAKDM4E | |
| SCHEMBL6850089 | 0.59 | PLK1 (0.44) | ALDH1A1MAPK1LMNAKDM4EMAPT | |
| SCHEMBL6850076 | 0.58 | MAPT (0.46) | ALDH1A1TSHRMAPK1LMNAKDM4E | |
| SCHEMBL6850114 | 0.58 | PLK1 (0.45) | ALDH1A1KDM4EMAPTHPGDMEN1 | |
| SCHEMBL6855784 | 0.58 | MAPT (0.46) | ALDH1A1TSHRMAPK1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6828315-B1 | Anti- inflammatories, anti-allergics, bronchodilatators, anti-asthmatics, or TNF alpha inhibitors | WARNER-LAMBERT LLC | 2004-12-07 | — | — | US | claimed |