SCHEMBL6858844

SCHEMBL6858844

Cc1ccc2c(c1)C=CC2[Zr](Cl)Cl

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 1/20 0.30
CHRNA4 P43681 1/20 0.30
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4777746 0.85 CHRNB2 (0.30) CHRNB2CHRNA4
SCHEMBL28225248 0.83 ACHE (0.31) CHRNB2CHRNA4ACHE
SCHEMBL27592186 0.83 ACHE (0.31) CHRNB2CHRNA4ACHE
SCHEMBL8167362 0.79
SCHEMBL10592968 0.77 BRD4 (0.42) ACHE
SCHEMBL28261877 0.75 ACHE (0.33) CHRNB2CHRNA4ACHE
SCHEMBL29476027 0.72 ACHE (0.35) CHRNB2CHRNA4ACHE
SCHEMBL8766062 0.72 ACHE (0.35) CHRNB2CHRNA4ACHE
SCHEMBL812667 0.72 HTR2A (0.38)
SCHEMBL24455618 0.71 CHRNB2 (0.36) CHRNB2CHRNA4ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6835698-B2 Mixture containing ethylene polymer IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2004-12-28 US disclosed
CN-1049899-C Process for the preparation of a bridged metallocene compound as well as a catalyst component and a process for the polymerization of olefins DSM NV (NL) 2000-03-01 CN disclosed
CN-1128272-A Process for the preparation of a bridged metallocene compound as well as a catalyst component and a process for the polymerization of olefins DSM NV (NL) 1996-08-07 CN disclosed
CN-1031278-C Modified polyolefin particles and process for preparation thereof MITSUI PETROCHEMICAL IND (JP) 1996-03-13 CN disclosed
EP-0324856-A1 PROCESS FOR POLYMERIZING OLEFIN MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1989-07-26 EP disclosed